PTENα, a PTEN isoform translated through alternative initiation, regulates mitochondrial function and energy metabolism (Q28238905)

1

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Shiming He

2

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Jingyi Yang

3

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Xinying Jia

4

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Pan Wang

5

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Xi Chen

6

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Zhong Zhang

7

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Xiajuan Zou

8

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Michael A McNutt

9

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Yuxin Yin

A secreted PTEN phosphatase that enters cells to alter signaling and survival

11

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language of work or name

English

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publication date

6 May 2014

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published in

Cell Metabolism

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volume

19

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issue

5

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page(s)

836-48

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cites work

1 reference

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Phosphorylation of mammalian cytochrome c and cytochrome c oxidase in the regulation of cell destiny: respiration, apoptosis, and human disease

20 March 2017

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Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner

20 March 2017

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The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway

20 March 2017

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Breaking the code of DNA binding specificity of TAL-type III effectors

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A simple cipher governs DNA recognition by TAL effectors

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

20 March 2017

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MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines

20 March 2017

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

20 March 2017

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

20 March 2017

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A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas

20 March 2017

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Translation initiation at non-AUG triplets in mammalian cells

20 March 2017

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Essential role for nuclear PTEN in maintaining chromosomal integrity

20 March 2017

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Pten is essential for embryonic development and tumour suppression

20 March 2017

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Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

20 March 2017

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Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

20 March 2017

1 reference

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Initiation of translation in prokaryotes and eukaryotes

7 April 2017

1 reference

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Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism.

7 April 2017

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CUG start codon generates thioredoxin/glutathione reductase isoforms in mouse testes

29 September 2017

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Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites

29 September 2017

1 reference

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DUSP1 is controlled by p53 during the cellular response to oxidative stress

29 September 2017

1 reference

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Update on the genetics of Parkinson's disease

29 September 2017

1 reference

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Improving de novo sequencing of peptides using a charged tag and C-terminal digestion

29 September 2017

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Mitogen-activated protein kinase phosphatase 2: a novel transcription target of p53 in apoptosis

29 September 2017

1 reference

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cAMP-dependent tyrosine phosphorylation of subunit I inhibits cytochrome c oxidase activity

29 September 2017

1 reference

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Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]

29 September 2017

1 reference

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PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression

29 September 2017

1 reference

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Mitochondrial oxidative phosphorylation system assembly in man: recent achievements

29 September 2017

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Presentation of out-of-frame peptide/MHC class I complexes by a novel translation initiation mechanism

29 September 2017

1 reference

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Protein sequencing by matrix-assisted laser desorption ionization-postsource decay-mass spectrometry analysis of the N-Tris(2,4,6-trimethoxyphenyl)phosphine-acetylated tryptic digests

29 September 2017

1 reference

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Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097321

Systemic elevation of PTEN induces a tumor-suppressive metabolic state

29 September 2017

1 reference

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Selective deletion of Pten in pancreatic beta cells leads to increased islet mass and resistance to STZ-induced diabetes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097321

Unconventional translation initiation of human trypsinogen 4 at a CUG codon with an N-terminal leucine. A possible means to regulate gene expression.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097321

High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4097321

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24768297

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2014.03.023

1 reference

release_vbrdq6i2freftig5iab4klsety

1368651

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vbrdq6i2freftig5iab4klsety

mapped directly with Wikidata item

24 November 2022

based on heuristic

1368651

1 reference

1 reference

1 reference