Pandemic influenza: a potential role for statins in treatment and prophylaxis (Q28246595)

Clinical Infectious Diseases

Europe PubMed Central

title

Pandemic influenza: a potential role for statins in treatment and prophylaxis (English)

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1

David S Fedson

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language of work or name

English

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publication date

15 July 2006

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published in

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volume

43

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page(s)

199-205

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issue

2

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cites work

Should treatment of sepsis include statins?

1 reference

12 December 2020

Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus.

1 reference

12 December 2020

Lethal H5N1 influenza viruses escape host anti-viral cytokine responses

1 reference

12 December 2020

Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin

1 reference

12 December 2020

Anti-inflammatory effects of statins: clinical evidence and basic mechanisms

1 reference

12 December 2020

Influenza virus neuraminidase contributes to secondary bacterial pneumonia

1 reference

12 December 2020

Preinfection systemic inflammatory markers and risk of hospitalization due to pneumonia

1 reference

12 December 2020

Influenza and cardiovascular disease: a new opportunity for prevention and the need for further studies

1 reference

12 December 2020

The effect of statins on mortality in patients with bacteremia

1 reference

12 December 2020

Role for Influenza Virus Envelope Cholesterol in Virus Entry and Infection

1 reference

12 December 2020

Statins inhibit HIV-1 infection by down-regulating Rho activity.

1 reference

12 December 2020

Pathogenesis of Hong Kong H5N1 influenza virus NS gene reassortants in mice: the role of cytokines and B- and T-cell responses

1 reference

12 December 2020

Chemokines in acute respiratory distress syndrome

1 reference

12 December 2020

Cytokine-mediated inflammation in acute lung injury

1 reference

12 December 2020

Can we predict septic shock in patients with hospital-acquired pneumonia?

1 reference

12 December 2020

Endotoxin-induced lung injury in mice: structural, functional, and biochemical responses.

1 reference

12 December 2020

Rapid Effect of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibition on Coronary Endothelial Function

1 reference

12 December 2020

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

1 reference

12 December 2020

The effect of prior statin use on 30-day mortality for patients hospitalized with community-acquired pneumonia.

1 reference

12 December 2020

Statin therapy is associated with fewer deaths in patients with bacteraemia

1 reference

12 December 2020

Novel strategies for the treatment of sepsis

1 reference

12 December 2020

Oseltamivir resistance during treatment of influenza A (H5N1) infection

1 reference

12 December 2020

Cytokine elaboration in critically ill infants with bacterial sepsis, necrotizing entercolitis, or sepsis syndrome: correlation with clinical parameters of inflammation and mortality

1 reference

12 December 2020

Infectious disease. Old drugs losing effectiveness against flu; could statins fill gap?

1 reference

12 December 2020

Statin use and mortality within 180 days after bacteremia: A population-based cohort study*

1 reference

12 December 2020

Symptom pathogenesis during acute influenza: interleukin-6 and other cytokine responses

1 reference

12 December 2020

Influenza and the winter increase in mortality in the United States, 1959-1999.

1 reference

12 December 2020

A role for hydroxy-methylglutaryl coenzyme a reductase in pulmonary inflammation and host defense.

1 reference

12 December 2020

Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis

1 reference

12 December 2020

Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans

1 reference

12 December 2020

Withdrawal of statin treatment abrogates stroke protection in mice

1 reference

12 December 2020

HMG-CoA reductase inhibitor simvastatin profoundly improves survival in a murine model of sepsis

1 reference

12 December 2020

Lipid rafts and membrane dynamics

1 reference

12 December 2020

Human serum from patients with septic shock activates transcription factors STAT1, IRF1, and NF-kappaB and induces apoptosis in human cardiac myocytes

1 reference

12 December 2020

The impact of prior outpatient ACE inhibitor use on 30-day mortality for patients hospitalized with community-acquired pneumonia

1 reference

12 December 2020

Re-emergence of fatal human influenza A subtype H5N1 disease

1 reference

12 December 2020

Prior statin therapy is associated with a decreased rate of severe sepsis

1 reference

12 December 2020

Severe acute respiratory syndrome and the innate immune responses: modulation of effector cell function without productive infection

1 reference

12 December 2020

The etiology of sepsis: turned inside out

1 reference

12 December 2020

Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury

1 reference

12 December 2020

Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense

1 reference

12 December 2020

Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins

1 reference

12 December 2020

Should angiotensin II receptor blockers and statins be combined?

1 reference

12 December 2020

Withdrawal of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors elicits oxidative stress and induces endothelial dysfunction in mice

1 reference

12 December 2020

High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

1 reference

12 December 2020

Influenza: emergence and control

1 reference

12 December 2020

No apoptotic deaths and different levels of inductions of inflammatory cytokines in alveolar macrophages infected with influenza viruses

1 reference

12 December 2020

LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: effects on proinflammatory mediators, metalloproteinases, NF-kappaB, and ICAM-1 expression

1 reference

12 December 2020

The epidemiology and clinical impact of pandemic influenza.

1 reference

12 December 2020

Effects of spironolactone on human blood mononuclear cells: mineralocorticoid receptor independent effects on gene expression and late apoptosis induction

1 reference

12 December 2020

Inflammation, immunity, and HMG-CoA reductase inhibitors: statins as antiinflammatory agents?

1 reference

12 December 2020

Elevated plasma levels of soluble TNF receptors are associated with morbidity and mortality in patients with acute lung injury

1 reference

12 December 2020

Genesis of a highly pathogenic and potentially pandemic H5N1 influenza virus in eastern Asia.

1 reference

12 December 2020

Vaccine development for an imminent pandemic: why we should worry, what we must do.

1 reference

12 December 2020

Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals

1 reference

12 December 2020

Pretreatment with simvastatin reduces lung injury related to intestinal ischemia-reperfusion in rats.

1 reference

12 December 2020

Preparing for pandemic vaccination: an international policy agenda for vaccine development.

1 reference

12 December 2020

Assembly and budding of influenza virus

1 reference

12 December 2020

Statins and sepsis in patients with cardiovascular disease: a population-based cohort analysis

1 reference

12 December 2020

The efficacy, effectiveness and cost-effectiveness of inactivated influenza virus vaccines

1 reference

12 December 2020

Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells

1 reference

12 December 2020

Active NF-kappaB signalling is a prerequisite for influenza virus infection.

1 reference

12 December 2020

Effect of statin use within the first 24 hours of admission for acute myocardial infarction on early morbidity and mortality

1 reference

12 December 2020

Statin treatment after onset of sepsis in a murine model improves survival

1 reference

12 December 2020

Influenza virus assembly and budding in raft-derived microdomains: a quantitative analysis of the surface distribution of HA, NA and M2 proteins

1 reference

12 December 2020

Statin, like aspirin, should be given as early as possible in patients with acute coronary syndrome

1 reference

12 December 2020

Short-term statin therapy improves cardiac function and symptoms in patients with idiopathic dilated cardiomyopathy

1 reference

12 December 2020

Animal models of sepsis: setting the stage

1 reference

12 December 2020

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury

1 reference

12 December 2020

Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice

1 reference

12 December 2020

Mass mortality of harbor seals: pneumonia associated with influenza A virus

1 reference

12 December 2020

Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina)

1 reference

12 December 2020

Innate immune recognition of viral infection

1 reference

12 December 2020

Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus.

1 reference

12 December 2020

p38 mitogen-activated protein kinase-dependent hyperinduction of tumor necrosis factor alpha expression in response to avian influenza virus H5N1.

1 reference

12 December 2020

Evidence for cytokine mediation of disease expression in adults experimentally infected with influenza A virus

1 reference

12 December 2020

Characterization of the reconstructed 1918 Spanish influenza pandemic virus

1 reference

12 December 2020

Updating the Accounts: Global Mortality of the 1918-1920 "Spanish" Influenza Pandemic

1 reference

12 December 2020

The cotton rat provides a useful small-animal model for the study of influenza virus pathogenesis.

1 reference

12 December 2020

S1P3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF.

1 reference

12 December 2020

Molecular pathogenesis of influenza A virus infection and virus-induced regulation of cytokine gene expression

1 reference

12 December 2020