Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells (Q28249125)

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English	Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells	scientific article

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13 February 2020

Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells (English)

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13 February 2020

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DNA mismatch repair

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Meyling H Cheok

5

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13 February 2020

Charles G. Mullighan

13

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13 February 2020

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Mary V Relling

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13 February 2020

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Barthelemy Diouf

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13 February 2020

Qing Cheng

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13 February 2020

Natalia F Krynetskaia

3

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13 February 2020

Wenjian Yang

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13 February 2020

Deqing Pei

6

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13 February 2020

Yiping Fan

7

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13 February 2020

Cheng Cheng

8

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13 February 2020

Evgeny Y Krynetskiy

9

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13 February 2020

Hui Geng

10

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13 February 2020

Siying Chen

11

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13 February 2020

William E Thierfelder

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13 February 2020

James R Downing

14

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13 February 2020

Peggy Hsieh

15

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13 February 2020

William E Evans

18

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13 February 2020

Ching-Hon Pui

16

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13 February 2020

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25 September 2011

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13 February 2020

Nature Medicine

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13 February 2020

17

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13 February 2020

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13 February 2020

1298-1303

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13 February 2020

Molecular origins of cancer: Molecular basis of colorectal cancer

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20 March 2017

CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity

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Role of class II phosphoinositide 3-kinase in cell signalling

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A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

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20 March 2017

hMutS alpha is protected from ubiquitin-proteasome-dependent degradation by atypical protein kinase C zeta phosphorylation

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20 March 2017

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

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20 March 2017

Mismatch repair deficiency associated with overexpression of the MSH3 gene

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20 March 2017

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

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20 March 2017

Mouse models for hereditary nonpolyposis colorectal cancer

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20 March 2017

Modulation of mismatch repair and genomic stability by miR-155

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22 April 2017

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

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7 April 2017

Regulation of translation initiation by FRAP/mTOR

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Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management

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29 September 2017

Microdeletions are a general feature of adult and adolescent acute lymphoblastic leukemia: Unexpected similarities with pediatric disease

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29 September 2017

DNA repair alterations in common pediatric malignancies.

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29 September 2017

Thiopurines in current medical practice: molecular mechanisms and contributions to therapy-related cancer

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29 September 2017

Constitutive deficiency in DNA mismatch repair

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29 September 2017

TSC1 stabilizes TSC2 by inhibiting the interaction between TSC2 and the HERC1 ubiquitin ligase.

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29 September 2017

Inherited susceptibility to colorectal cancer

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29 September 2017

Degadration of mismatch repair hMutSalpha heterodimer by the ubiquitin-proteasome pathway

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29 September 2017

Germline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers.

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29 September 2017

Functional interactions and signaling properties of mammalian DNA mismatch repair proteins

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29 September 2017

TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth

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29 September 2017

Evidence for Msh2 haploinsufficiency in mice revealed by MNU-induced sister-chromatid exchange analysis

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29 September 2017

Epigenetic phenotypes distinguish microsatellite-stable and -unstable colorectal cancers

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29 September 2017

Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation

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29 September 2017

Protein phosphatase 2A is a critical regulator of protein kinase C zeta signaling targeted by SV40 small t to promote cell growth and NF-kappaB activation

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29 September 2017

The role of DNA mismatch repair in platinum drug resistance

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29 September 2017

Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage

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29 September 2017

Induction of two DNA mismatch repair proteins, MSH2 and MSH6, in differentiated human neuroblastoma SH-SY5Y cells exposed to doxorubicin.

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2 June 2018

Msh2 deficiency attenuates but does not abolish thiopurine hematopoietic toxicity in msh2-/- mice

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21 January 2018

Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine.

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21 January 2018

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.

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21 January 2018

Mismatch G-T binding activity and MSH2 expression is quantitatively related to sensitivity of cells to methylating agents.

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21 January 2018

Acute lymphoblastic leukemia

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12 December 2020

based on heuristic

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Microsatellite instability and p53 mutations are associated with abnormal expression of the MSH2 gene in adult acute leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21946537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of DNA mismatch repair proteins in acute lymphoblastic leukaemia and normal bone marrow

1 reference

https://pubmed.ncbi.nlm.nih.gov/21946537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NM.2430

2 references

Consolidated OpenCitations Corpus – April 2017

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13 February 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21946537%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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13 February 2020

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