Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy (Q28260415)

1

0 references

Grace W Chen

2

0 references

Jennifer M Pearson

3

0 references

Joseph S Sandhorst

4

0 references

Martin S Hoagland

5

0 references

Jung-Taek Kwon

6

0 references

Soon-Kyung Hwang

7

0 references

Hua Jin

8

0 references

Mona I Churchwell

9

0 references

Daniel R Doerge

11

0 references

William G Helferich

12

0 references

Paul J Hergenrother

Characterization of the interleukin-1beta-converting enzyme/ced-3-family protease, caspase-3/CPP32, in Hodgkin's disease: lack of caspase-3 expression in nodular lymphocyte predominance Hodgkin's disease

13

0 references

language of work or name

English

0 references

publication date

October 2006

0 references

published in

Nature Chemical Biology

0 references

volume

2

0 references

issue

10

0 references

page(s)

543-50

0 references

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Intrinsic tumour suppression

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Achilles' heel of cancer?

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Protein hijacking: key proteins held captive against their will

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Targeting the FLICE Inhibitory Protein (FLIP) in cancer therapy.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Pathways of apoptotic and non-apoptotic death in tumour cells

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Medicine. Targeting apoptotic pathways in cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Pharmacological manipulation of cell death: clinical applications in sight?

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Rational design and real time, in-cell detection of the proapoptotic activity of a novel compound targeting Bcl-X(L).

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

A small molecule Smac mimic potentiates TRAIL- and TNFalpha-mediated cell death

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Direct activation of the apoptosis machinery as a mechanism to target cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Mechanisms of caspase activation

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Maintenance of caspase-3 proenzyme dormancy by an intrinsic "safety catch" regulatory tripeptide

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Elevated procaspase levels in human melanoma

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Overexpression of caspase-3 in hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Components of the cell death machine and drug sensitivity of the National Cancer Institute Cell Line Panel.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Mutations in the Procaspase-3 Dimer Interface Affect the Activity of the Zymogen

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Pro-caspase-3 is a major physiologic target of caspase-8.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Human caspase-7 activity and regulation by its N-terminal peptide.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Direct Quantitation of Poly(ADP-Ribose) Polymerase (PARP) Activity as a Means to Distinguish Necrotic and Apoptotic Death in Cell and Tissue Samples

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Role of caspase 3-dependent Bcl-2 cleavage in potentiation of apoptosis by Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Antisense bcl-2 treatment increases programmed cell death in non-small cell lung cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Expression of caspases 3, 6 and 8 is increased in parallel with apoptosis and histological aggressiveness of the breast lesion

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021

Down-regulation of caspase 3 in breast cancer: a possible mechanism for chemoresistance

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO814

7 January 2021