Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose (Q28261829)

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29 December 2019

title

Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose (English)

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29 December 2019

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5

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Fabio Vistoli

9

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Stefano Del Prato

11

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Piero Marchetti

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29 December 2019

author name string

S Del Guerra

1

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M Grupillo

2

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M Masini

3

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R Lupi

4

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S Torri

6

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U Boggi

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M Del Chiaro

8

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F Mosca

10

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language of work or name

English

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publication date

1 March 2007

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Diabetes - Metabolism: Research and Reviews

29 December 2019

published in

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volume

23

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29 December 2019

issue

3

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29 December 2019

page(s)

234-238

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Beta cell function and its relation to insulin action in humans: a critical appraisal

29 December 2019

cites work

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7 January 2021

Global and societal implications of the diabetes epidemic

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7 January 2021

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

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Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

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Oral antihyperglycemic therapy for type 2 diabetes: scientific review

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New trends in the development of oral antidiabetic drugs

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Population PKPD modelling of the long-term hypoglycaemic effect of gliclazide given as a once-a-day modified release (MR) formulation.

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Gliclazide modified release

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Sulphonylurea action revisited: the post-cloning era.

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7 January 2021

In vitro and in vivo antioxidant properties of gliclazide.

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7 January 2021

Free radical scavenging activity of sulfonylureas: a clinical assessment of the effect of gliclazide

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7 January 2021

Gliclazide improves anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes.

1 reference

7 January 2021

Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

1 reference

7 January 2021

Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

1 reference

7 January 2021

Functional and molecular defects of pancreatic islets in human type 2 diabetes

1 reference

7 January 2021

Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients.

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7 January 2021

Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.

1 reference

7 January 2021

Pharmacokinetic-pharmacodynamic relationships of oral hypoglycaemic agents. An update

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7 January 2021

Effect of rifampin on the pharmacokinetics and pharmacodynamics of gliclazide

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7 January 2021

A radical explanation for glucose-induced beta cell dysfunction

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7 January 2021

Insights from a successful case of intrahepatic islet transplantation into a type 1 diabetic patient.

1 reference

7 January 2021

The biguanide compound metformin prevents desensitization of human pancreatic islets induced by high glucose

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7 January 2021

A common polymorphism in the promoter of UCP2 contributes to the variation in insulin secretion in glucose-tolerant subjects

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7 January 2021

Intermittent high glucose enhances apoptosis related to oxidative stress in human umbilical vein endothelial cells: the role of protein kinase C and NAD(P)H-oxidase activation

1 reference

7 January 2021

Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients.

1 reference

7 January 2021

Sulfonylurea induced beta-cell apoptosis in cultured human islets

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7 January 2021

Effects of prolonged in vitro exposure to sulphonylureas on the function and survival of human islets

1 reference

7 January 2021

Gliclazide protects pancreatic beta-cells from damage by hydrogen peroxide

1 reference

7 January 2021

Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection

1 reference

7 January 2021

Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes

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7 January 2021

Therapeutical concentrations of tolbutamide, glibenclamide, gliclazide and gliquidone at different glucose levels: in vitro effects on pancreatic A- and B-cell function

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7 January 2021

Secondary sulfonylurea failure: comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide

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7 January 2021

Pioglitazone elicits long-term improvements in insulin sensitivity in patients with type 2 diabetes: comparisons with gliclazide-based regimens

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7 January 2021

Identifiers

DOI

10.1002/DMRR.680

1 reference

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29 December 2019

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