Nuclear receptor coactivators: the key to unlock chromatin (Q28266740)

Biochemistry and Cell Biology

Europe PubMed Central

title

Nuclear receptor coactivators: the key to unlock chromatin (English)

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author name string

Wei Xu

series ordinal

1

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language of work or name

English

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publication date

August 2005

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published in

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volume

83

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issue

4

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page(s)

418-28

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cites work

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Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53

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Coordinate regulation of transcription and splicing by steroid receptor coregulators

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The Drosophila orphan nuclear receptor DHR38 mediates an atypical ecdysteroid signaling pathway

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Methylation at arginine 17 of histone H3 is linked to gene activation

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ATP-dependent nucleosome remodeling

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Nuclear receptors: a rendezvous for chromatin remodeling factors

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Targeting of SWI/SNF chromatin remodelling complexes to estrogen-responsive genes

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FACT facilitates transcription-dependent nucleosome alteration

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The histone acetylase PCAF is a nuclear receptor coactivator.

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Nucleosomes unfold completely at a transcriptionally active promoter.

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Differential effect of small ubiquitin-like modifier (SUMO)-ylation of the androgen receptor in the control of cooperativity on selective versus canonical response elements

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Role of CBP/P300 in nuclear receptor signalling

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A viral mechanism for inhibition of p300 and PCAF acetyltransferase activity

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Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

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Regulation of transcription by a protein methyltransferase

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Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase

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Control of CBP co-activating activity by arginine methylation

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Structure and specificity of nuclear receptor-coactivator interactions

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Ligand-independent coactivation of ERalpha AF-1 by steroid receptor RNA activator (SRA) via MAPK activation

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Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators

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Two-step synergism between the progesterone receptor and the DNA-binding domain of nuclear factor 1 on MMTV minichromosomes.

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ATP-driven chromatin remodeling activity and histone acetyltransferases act sequentially during transactivation by RAR/RXR In vitro.

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BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation

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A kinetic framework for a mammalian RNA polymerase in vivo

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Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex

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AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor

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Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

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Tip60 is a co-activator specific for class I nuclear hormone receptors

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Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis

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Identification of a new class of steroid hormone receptors

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Interaction of the Ubc9 human homologue with c-Jun and with the glucocorticoid receptor

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

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BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation

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TIP30 interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates c-myc transcription

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The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome

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Synergistic enhancement of nuclear receptor function by p160 coactivators and two coactivators with protein methyltransferase activities

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Biochemical analysis of distinct activation functions in p300 that enhance transcription initiation with chromatin templates

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A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex

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Evidence for nucleosome depletion at active regulatory regions genome-wide

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Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination

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Ribozyme targeting demonstrates that the nuclear receptor coactivator AIB1 is a rate-limiting factor for estrogen-dependent growth of human MCF-7 breast cancer cells.

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The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation

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ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance

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Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter

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The RXR heterodimers and orphan receptors

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Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor

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Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

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Combinatorial control of gene expression by nuclear receptors and coregulators

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Minireview: nuclear receptor coactivators--an update

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The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

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Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter

21 January 2018

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ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex

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Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1

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Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations

21 January 2018

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Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling

21 January 2018

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Cooperation between complexes that regulate chromatin structure and transcription

21 January 2018

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A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex

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The transcriptional coactivators p300 and CBP are histone acetyltransferases

21 January 2018

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Histone-like TAFs within the PCAF histone acetylase complex

21 January 2018

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Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification

21 January 2018

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Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer

21 January 2018

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Ubc9 interacts with the androgen receptor and activates receptor-dependent transcription

21 January 2018

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The role of corepressors in transcriptional regulation by nuclear hormone receptors

21 January 2018

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Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

21 January 2018

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A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system

21 January 2018

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Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling

21 January 2018

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Histones are first hyperacetylated and then lose contact with the activated PHO5 promoter.

21 January 2018

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Histone methylation versus histone acetylation: new insights into epigenetic regulation

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CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant

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Steroid receptor coactivator-1 is a histone acetyltransferase

21 January 2018

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Biological control through regulated transcriptional coactivators

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Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes

21 January 2018

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Activation of nuclear receptor coactivator PGC-1alpha by arginine methylation

21 January 2018

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Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor

21 January 2018

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Co-activators and co-repressors in the integration of transcriptional responses

21 January 2018

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DNA instructed displacement of histones H2A and H2B at an inducible promoter

21 January 2018

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The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

21 January 2018

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Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha

21 January 2018

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Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor

21 January 2018

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Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors

21 January 2018

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Use of chromatin immunoprecipitation to clone novel E2F target promoters

21 January 2018

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Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways

21 January 2018

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Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2

21 January 2018

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Molecular mechanisms and cellular biology of the steroid receptor coactivator (SRC) family in steroid receptor function

21 January 2018

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A transcriptional switch mediated by cofactor methylation

21 January 2018

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A methylation-mediator complex in hormone signaling

21 January 2018

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RETRACTED: Nuclear Receptor Function Requires a TFTC-Type Histone Acetyl Transferase Complex

21 January 2018

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A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

21 January 2018

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Roles of SWI1, SWI2, and SWI3 proteins for transcriptional enhancement by steroid receptors

21 January 2018

1 reference

Differential gene regulation by the SRC family of coactivators

21 January 2018

1 reference

Regulation of nuclear receptor activity by a pseudouridine synthase through posttranscriptional modification of steroid receptor RNA activator

21 January 2018

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