Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1) (Q28268852)

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30 December 2019

title

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1) (English)

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30 December 2019

7

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30 December 2019

author name string

Akiyoshi Komuro

1

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30 December 2019

Takeshi Imamura

2

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30 December 2019

Masao Saitoh

3

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30 December 2019

Yoko Yoshida

4

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30 December 2019

Takao Yamori

5

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30 December 2019

Kohei Miyazono

6

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30 December 2019

language of work or name

English

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publication date

1 September 2004

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30 December 2019

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30 December 2019

volume

23

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30 December 2019

issue

41

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30 December 2019

page(s)

6914-6923

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Smads as transcriptional co-modulators

30 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Lung Krüppel-like factor contains an autoinhibitory domain that regulates its transcriptional activation by binding WWP1, an E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Smads: transcriptional activators of TGF-beta responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Alternative splicing determines the domain structure of WWP1, a Nedd4 family protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

A HECT domain ubiquitin ligase closely related to the mammalian protein WWP1 is essential for Caenorhabditis elegans embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Smad6 inhibits signalling by the TGF-beta superfamily.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Potential role of WAF1/Cip1/p21 as a mediator of TGF-beta cytoinhibitory effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Endogenous TGF-beta signaling suppresses maturation of osteoblastic mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

TGFbeta signaling in growth control, cancer, and heritable disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Two major Smad pathways in TGF-beta superfamily signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Identification of novel human WW domain-containing proteins by cloning of ligand targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

Characterization of Human hect Domain Family Members and Their Interaction with UbcH5 and UbcH7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207885

21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1207885

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15221015%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

30 December 2019

0 references

1 reference

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