Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway (Q28269044)

https://api.crossref.org/works/10.1074%2FJBC.M506460200

DNA damage-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Cell-cycle checkpoints and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Principles of tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

rad-dependent response of the chk1-encoded protein kinase at the DNA damage checkpoint.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Chk1 is haploinsufficient for multiple functions critical to tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Human claspin is required for replication checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Mrc1 transduces signals of DNA replication stress to activate Rad53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Claspin and the activated form of ATR-ATRIP collaborate in the activation of Chk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

DNA binding domain in the replication checkpoint protein Mrc1 of Schizosaccharomyces pombe

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

DNA-dependent phosphorylation of Chk1 and Claspin in a human cell-free system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Phosphorylated claspin interacts with a phosphate-binding site in the kinase domain of Chk1 during ATR-mediated activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Adaptation of a DNA replication checkpoint response depends upon inactivation of Claspin by the Polo-like kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Response of Xenopus Cds1 in cell-free extracts to DNA templates with double-stranded ends

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Cleavage and inactivation of ATM during apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Specificity and mechanism of action of some commonly used protein kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Caspase-7 expanded function and intrinsic expression level underlies strain-specific brain phenotype of caspase-3-null mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Caspase knockouts: matters of life and death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Caspase-7 gene disruption reveals an involvement of the enzyme during the early stages of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200

Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M506460200