UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects (Q28290319)

An alternative promoter contributes to tissue- and inducer-specific expression of the rat UDP-glucuronosyltransferase 1A6 gene

Europe PubMed Central

title

UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects (English)

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author name string

Karl Walter Bock

series ordinal

1

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Christoph Köhle

series ordinal

2

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language of work or name

English

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publication date

2005

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published in

Methods in Enzymology

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volume

400

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page(s)

57-75

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cites work

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Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate

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Frequent co-occurrence of the TATA box mutation associated with Gilbert’s syndrome (UGT1A1*28) with other polymorphisms of the UDP-glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians

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Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6.

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