HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks (Q28297459)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16479169%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

review article

1 reference

title

HEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networks (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16479169%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

0 references

1

1 reference

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16 January 2020

author name string

Erica A Golemis

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16479169%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

language of work or name

English

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publication date

15 February 2006

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16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16479169%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

5

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16 January 2020

issue

4

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16 January 2020

page(s)

384-391

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HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells

16 January 2020

cites work

1 reference

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20 March 2017

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The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

20 March 2017

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Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance

20 March 2017

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Cilia and the cell cycle?

20 March 2017

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Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53

20 March 2017

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20 March 2017

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Crk-associated substrate (Cas) family member, NEDD9, is regulated in human neuroblastoma cells and in the embryonic hindbrain by all-trans retinoic acid

20 March 2017

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Cell Polarity and the Cytoskeleton in theCaenorhabditis ElegansZygote

20 March 2017

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Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells

20 March 2017

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Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

20 March 2017

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Nek2A kinase stimulates centrosome disjunction and is required for formation of bipolar mitotic spindles

20 March 2017

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AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

20 March 2017

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Active cyclin B1-Cdk1 first appears on centrosomes in prophase

20 March 2017

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Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function

20 March 2017

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Epithelial-mesenchymal transitions in tumour progression

20 March 2017

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Regulation of HEF1 expression and phosphorylation by TGF-beta 1 and cell adhesion

20 March 2017

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The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles

20 March 2017

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Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

20 March 2017

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Functions of the adapter protein Cas: signal convergence and the determination of cellular responses

20 March 2017

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20 March 2017

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Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2

20 March 2017

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Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics

20 March 2017

1 reference

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alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells

20 March 2017

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A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1

20 March 2017

1 reference

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Modification of the composition of polycystin-1 multiprotein complexes by calcium and tyrosine phosphorylation

20 March 2017

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Zyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressor

20 March 2017

1 reference

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Crk-associated substrate p130(Cas) interacts with nephrocystin and both proteins localize to cell-cell contacts of polarized epithelial cells

20 March 2017

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Integrin signalling: a new Cas(t) of characters enters the stage

20 March 2017

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BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells

20 March 2017

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Cyclin-dependent kinase control of centrosome duplication

20 March 2017

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Multinuclearity and increased ploidy caused by overexpression of the aurora- and Ipl1-like midbody-associated protein mitotic kinase in human cancer cells

20 March 2017

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20 March 2017

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A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

20 March 2017

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Cell cycle-regulated processing of HEF1 to multiple protein forms differentially targeted to multiple subcellular compartments

20 March 2017

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CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

20 March 2017

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Kar9p is a novel cortical protein required for cytoplasmic microtubule orientation in yeast

20 March 2017

1 reference

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A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators.

20 March 2017

1 reference

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Regulation of integrin-mediated p130(Cas) tyrosine phosphorylation in human B cells. A role for p59(Fyn) and SHP2

20 March 2017

1 reference

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Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes

20 March 2017

1 reference

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Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae

20 March 2017

1 reference

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Molecular cloning of a cDNA encoding a phosphoprotein, Efs, which contains a Src homology 3 domain and associates with Fyn

20 March 2017

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A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner

20 March 2017

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Proline-rich sequences that bind to Src homology 3 domains with individual specificities

20 March 2017

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Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates

20 March 2017

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Chfr is required for tumor suppression and Aurora A regulation

20 March 2017

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A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry

20 March 2017

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Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

20 March 2017

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Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis

20 March 2017

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Genes that mediate breast cancer metastasis to lung

20 March 2017

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7 April 2017

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PDGFRalphaalpha signaling is regulated through the primary cilium in fibroblasts

7 April 2017

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Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

7 April 2017

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Epithelial-mesenchymal transitions in development and pathologies

7 April 2017

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Taking cell-matrix adhesions to the third dimension

7 April 2017

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Rho GTPases control polarity, protrusion, and adhesion during cell movement

7 April 2017

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Asymmetric cell divisions promote stratification and differentiation of mammalian skin

7 April 2017

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Centrosome composition and microtubule anchoring mechanisms

7 April 2017

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Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

7 April 2017

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7 April 2017

Pak GITs to Aurora-A.

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The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A.

29 September 2017

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Centrosomes in cellular regulation

29 September 2017

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Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis.

29 September 2017

1 reference

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Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization.

29 September 2017

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Smad4 dependency defines two classes of transforming growth factor {beta} (TGF-{beta}) target genes and distinguishes TGF-{beta}-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses

29 September 2017

1 reference

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Aurora kinases: shining lights on the therapeutic horizon?

29 September 2017

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Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells

29 September 2017

1 reference

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Centrosome control of the cell cycle

29 September 2017

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Conditional transgenic system for mouse aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein

29 September 2017

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Aurora kinases, aneuploidy and cancer, a coincidence or a real link?

29 September 2017

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The centrosome in human genetic disease

29 September 2017

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AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner.

29 September 2017

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Aurora-A - a guardian of poles

29 September 2017

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Prespecification and plasticity: shifting mechanisms of cell migration

29 September 2017

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Parsing the polarity code

29 September 2017

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Cdk5 phosphorylation of FAK regulates centrosome-associated miocrotubules and neuronal migration.

29 September 2017

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Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases

29 September 2017

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Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer.

29 September 2017

1 reference

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The GDP exchange factor AND-34 is expressed in B cells, associates with HEF1, and activates Cdc42.

29 September 2017

1 reference

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Microtubule release from the centrosome in migrating cells

29 September 2017

1 reference

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beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

29 September 2017

1 reference

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The Nek2 protein kinase: a novel regulator of centrosome structure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

On the role of aurora-A in centrosome function

29 September 2017

1 reference

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Cas, Fak and Pyk2 function in diverse signaling cascades to promote Yersinia uptake.

29 September 2017

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29 September 2017

1 reference

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Centrosome reorientation in wound-edge cells is cell type specific

29 September 2017

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Centrosome behavior in motile HGF-treated PtK2 cells expressing GFP-gamma tubulin

29 September 2017

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Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progression

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Bazooka is required for localization of determinants and controlling proliferation in the sensory organ precursor cell lineage in Drosophila

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Tamoxifen resistance in breast cancer: elucidating mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

The centrosome in vertebrates: more than a microtubule-organizing center

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Paxillin-ARF GAP signaling and the cytoskeleton

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Control of spindle polarity and orientation in Saccharomyces cerevisiae.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

New insights: nephronophthisis-medullary cystic kidney disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Centrosome-dependent exit of cytokinesis in animal cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

29 September 2017

Centrosome maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Regulation of c-SRC activity and function by the adapter protein CAS

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Matrix survival signaling: from fibronectin via focal adhesion kinase to c-Jun NH(2)-terminal kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Cas mediates transcriptional activation of the serum response element by Src.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Dynamic association of proteasomal machinery with the centrosome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Dissociation of FAK/p130(CAS)/c-Src complex during mitosis: role of mitosis-specific serine phosphorylation of FAK

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Pericentrin and gamma-tubulin form a protein complex and are organized into a novel lattice at the centrosome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Centrosome positioning and directionality of cell movements.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

An aurora kinase is essential for flagellar disassembly in Chlamydomonas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Timing of cyclin D1 expression within G1 phase is controlled by Rho.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Adherens junctions inhibit asymmetric division in the Drosophila epithelium

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

BCAR1/p130Cas expression in untreated and acquired tamoxifen-resistant human breast carcinomas.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

The epithelial cell default-phenotype hypothesis and its implications for cancer

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Multinucleation and inhibition of cytokinesis in suspended cells: reversal upon reattachment to a substrate

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Localization of the E1B proteins of adenovirus 5 in transformed cells, as revealed by interaction with monoclonal antibodies.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Fibronectin mediates cytokinesis and growth of rat follicular cells in serum-free medium

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

The extracellular matrix guides the orientation of the cell division axis.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Centrosome localization determines neuronal polarity.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

The roles of Fzy/Cdc20 and Fzr/Cdh1 in regulating the destruction of cyclin B in space and time

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Dissection of HEF1-dependent functions in motility and transcriptional regulation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2547350

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

27 November 2018

1 reference

12 December 2020

A novel mechanism for activation of the protein kinase Aurora A

1 reference

12 December 2020

Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast

1 reference

12 December 2020

Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer

1 reference

12 December 2020

Identifiers

DOI

10.4161/CC.5.4.2439

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16479169%20AND%20SRC:MED&resulttype=core&format=json

release_4djne5jwprdv3me27r742xfa3q

16 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4djne5jwprdv3me27r742xfa3q

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16479169%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference