Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models (Q45103581)

9 December 2017

Cre-loxP-controlled periodic Aurora-A overexpression induces mitotic abnormalities and hyperplasia in mammary glands of mouse models (English)

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9 December 2017

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Dongwei Zhang

1

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9 December 2017

Toru Hirota

2

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9 December 2017

Tomotoshi Marumoto

3

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9 December 2017

Michio Shimizu

4

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9 December 2017

Naoko Kunitoku

5

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9 December 2017

Takashi Sasayama

6

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9 December 2017

Yoshimi Arima

7

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9 December 2017

Liping Feng

8

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9 December 2017

Misao Suzuki

9

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9 December 2017

Motohiro Takeya

10

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9 December 2017

Hideyuki Saya

11

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9 December 2017

language of work or name

English

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publication date

1 November 2004

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9 December 2017

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9 December 2017

23

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9 December 2017

54

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9 December 2017

8720-8730

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208153

9 December 2017

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cites work

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

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Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.

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Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss.

21 January 2018

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A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

21 January 2018

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The Aurora/Ipl1p kinase family: regulators of chromosome segregation and cytokinesis.

21 January 2018

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Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells

21 January 2018

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Genetic instability and darwinian selection in tumours

21 January 2018

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The comparative pathology of human and mouse mammary glands

21 January 2018

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21 January 2018

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Suppression of the STK15 oncogenic activity requires a transactivation-independent p53 function

21 January 2018

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Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

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Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human

21 January 2018

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Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

21 January 2018

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Mediation of c-Myc-induced apoptosis by p53.

21 January 2018

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Aurora-A and an interacting activator, the LIM protein Ajuba, are required for mitotic commitment in human cells

21 January 2018

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Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

21 January 2018

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Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase

21 January 2018

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Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

21 January 2018

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Genetic instabilities in human cancers

21 January 2018

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G1 tetraploidy checkpoint and the suppression of tumorigenesis

21 January 2018

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Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells.

21 January 2018

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Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells

21 January 2018

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Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 January 2018

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Association of centrosomal kinase STK15/BTAK mRNA expression with chromosomal instability in human breast cancers

21 January 2018

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Mitotic kinases as regulators of cell division and its checkpoints

21 January 2018

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Tumour-amplified kinase BTAK is amplified and overexpressed in gastric cancers with possible involvement in aneuploid formation

21 January 2018

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A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

21 January 2018

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Cell cycle progression after cleavage failure: mammalian somatic cells do not possess a "tetraploidy checkpoint".

21 January 2018

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Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

21 January 2018

1 reference

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Cre-mediated gene deletion in the mammary gland

21 January 2018

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Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.

21 January 2018

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Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

21 January 2018

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Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

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Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208153

inferred from DOI database lookup

7 January 2021

based on heuristic

Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208153

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1208153

1 reference

Dimensions Publication ID

9 December 2017

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1 reference