Proteasomes activate aggresome disassembly and clearance by producing unanchored ubiquitin chains (Q28298487)

1

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Priyaanka Nanduri

2

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Yanhua Rao

3

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R Scott Panichelli

4

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Akihiro Ito

5

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Tso-Pang Yao

Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini

7

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language of work or name

English

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publication date

26 September 2013

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published in

Molecular Cell

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volume

51

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issue

6

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page(s)

819-28

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cites work

1 reference

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Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

20 March 2017

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Non-muscle myosin II takes centre stage in cell adhesion and migration

20 March 2017

1 reference

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Direct activation of protein kinases by unanchored polyubiquitin chains

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

K63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

Histone deacetylase 6 regulates growth factor-induced actin remodeling and endocytosis

20 March 2017

1 reference

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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

20 March 2017

1 reference

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Solution structure of the Ubp-M BUZ domain, a highly specific protein module that recognizes the C-terminal tail of free ubiquitin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

The JAMM motif of human deubiquitinase Poh1 is essential for cell viability

20 March 2017

1 reference

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The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

20 March 2017

1 reference

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The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

A cryptic protease couples deubiquitination and degradation by the proteasome

20 March 2017

1 reference

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Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome

20 March 2017

1 reference

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HDAC6 is a microtubule-associated deacetylase

20 March 2017

1 reference

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Aggresomes: a cellular response to misfolded proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

Aggresomes, inclusion bodies and protein aggregation

20 March 2017

1 reference

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HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

The role of ubiquitin in autophagy-dependent protein aggregate processing

9 May 2017

1 reference

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Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

HDAC6 modulates cell motility by altering the acetylation level of cortactin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

The polyglutamine neurodegenerative protein ataxin 3 regulates aggresome formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

Inefficient degradation of truncated polyglutamine proteins by the proteasome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

Failure of the ubiquitin-proteasome system in Parkinson's disease

29 September 2017

1 reference

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Aggregates in neurodegenerative disease: crowds and power?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

Dynamic association of proteasomal machinery with the centrosome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

Global changes to the ubiquitin system in Huntington's disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

α-Synuclein Is Degraded by Both Autophagy and the Proteasome

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3791850

10.1016/J.MOLCEL.2013.08.016

27 November 2018

Identifiers

DOI

1 reference

1293898

1293898

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1 reference

1 reference