Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2 (Q28299947)

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English	Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2	scientific article

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title

Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2 (English)

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James K Chen

5

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Robert Lefkowitz

series ordinal

8

object named as

Robert J Lefkowitz

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author name string

Wei Chen

series ordinal

1

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Xiu-Rong Ren

series ordinal

2

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Christopher D Nelson

series ordinal

3

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Larry S Barak

series ordinal

4

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Philip A Beachy

series ordinal

6

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Frederic de Sauvage

series ordinal

7

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language of work or name

English

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publication date

24 December 2004

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published in

Science

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volume

306

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page(s)

2257-60

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issue

5705

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cites work

'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors

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Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis*

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https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

Identification of a Functional Interaction between the Transmembrane Protein Smoothened and the Kinesin-Related Protein Costal2

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer

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https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

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https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

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https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

Patched acts catalytically to suppress the activity of Smoothened

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

The hedgehog signaling network

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https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

Identification of a palmitic acid-modified form of human Sonic hedgehog

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Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

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Smoothened activates Galphai-mediated signaling in frog melanophores

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https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

G protein-coupled receptor kinases

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

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Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

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Activating Smoothened mutations in sporadic basal-cell carcinoma

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The developmental biology of brain tumors.

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Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway.

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Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog

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Hedgehog signaling in animal development: paradigms and principles

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Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail

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https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation

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https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

The seven-transmembrane receptor smoothened cell-autonomously induces multiple ventral cell types

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https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

Small molecule modulation of Smoothened activity

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1104135

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DOI

10.1126/SCIENCE.1104135

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stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4785364

OpenCitations bibliographic resource ID

4785364

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

4785364

Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2 (Q28299947)

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Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2 (Q28299947)

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