DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors (Q28303693)

Luis A Diaz

12

0 references

Victor Velculescu

Victor E Velculescu

11

0 references

Kenneth W. Kinzler

14

Kenneth W Kinzler

0 references

Ralph H. Hruban

15

Ralph H Hruban

0 references

Christopher L Wolfgang

9

Christopher L Wolfgang

0 references

Anirban Maitra

6

Anirban Maitra

0 references

Richard D Schulick

7

Richard D Schulick

0 references

David S Klimstra

5

David S Klimstra

0 references

Barish H Edil

3

Barish H Edil

0 references

Nickolas Papadopoulos

16

Nickolas Papadopoulos

0 references

Michael A Choti

10

Michael A Choti

0 references

Yuchen Jiao

1

Yuchen Jiao

0 references

Chanjuan Shi

2

Chanjuan Shi

0 references

Laura A Tang

8

Laura H Tang

0 references

author name string

Roeland F de Wilde

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

4

0 references

language of work or name

English

0 references

publication date

4 March 2011

0 references

published in

Science

0 references

volume

331

0 references

page(s)

1199-203

0 references

issue

6021

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Distinct factors control histone variant H3.3 localization at specific genomic regions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Defining the role of mTOR in cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Targeting the phosphoinositide 3-kinase pathway in cancer

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Ras, PI(3)K and mTOR signalling controls tumour cell growth

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Molecular basis of the mixed lineage leukemia-menin interaction: implications for targeting mixed lineage leukemias

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Gene Amplifications in Well-Differentiated Pancreatic Neuroendocrine Tumors Inactivate the p53 Pathway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Pancreatic endocrine tumors: expression profiling evidences a role for AKT-mTOR pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Endocrine neoplasms of the pancreas: pathologic and genetic features

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Chromosomal alterations detected by comparative genomic hybridization in nonfunctioning endocrine pancreatic tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Neuronal subtype identity in the rat auditory brainstem as defined by molecular profile and axonal projection

29 September 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1200609

Prognostic factors and survival in 324 patients with pancreatic endocrine tumor treated at a single institution

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1200609

Malignant pancreatic endocrine tumor in a child with tuberous sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1200609

MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1200609

Colorectal cancer: mutations in a signalling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1200609

Mutations in the chromatin-associated protein ATRX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1200609

ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1200609

Localization of putative tumor suppressor loci by genome-wide allelotyping in human pancreatic endocrine tumors.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144496

Menin, a tumor suppressor, represses JunD-mediated transcriptional activity by association with an mSin3A-histone deacetylase complex

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21252315

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1200609

1 reference

652309

652309

1 reference

1 reference

1 reference