Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions (Q28347865)

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English	Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions	scientific article

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3 November 2019

Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions (English)

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3 November 2019

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S Bae

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J Seong

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Y Paik

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1 February 2001

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Biochemical Journal

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689-699

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3 November 2019

Pt 3

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3 November 2019

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

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Mutations in the gene encoding 3 beta-hydroxysteroid-delta 8, delta 7-isomerase cause X-linked dominant Conradi-Hünermann syndrome

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Histidine77, glutamic acid81, glutamic acid123, threonine126, asparagine194, and tryptophan197 of the human emopamil binding protein are required for in vivo sterol delta 8-delta 7 isomerization

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The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8

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Cholesterol biosynthesis from lanosterol: development of a novel assay method and characterization of rat liver microsomal lanosterol delta 24-reductase

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The mysteries of sigma receptors: new family members reveal a role in cholesterol synthesis

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20 March 2017

Cholesterol biosynthesis from lanosterol. Molecular cloning, tissue distribution, expression, chromosomal localization, and regulation of rat 7-dehydrocholesterol reductase, a Smith-Lemli-Opitz syndrome-related protein

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20 March 2017

Emopamil-binding protein, a mammalian protein that binds a series of structurally diverse neuroprotective agents, exhibits delta8-delta7 sterol isomerase activity in yeast

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20 March 2017

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A receptor-mediated pathway for cholesterol homeostasis

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Isolation and characterization of an Arabidopsis thaliana C-8,7 sterol isomerase: functional and structural similarities to mammalian C-8,7 sterol isomerase/emopamil-binding protein

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Antiproliferative effects of SR31747A in animal cell lines are mediated by inhibition of cholesterol biosynthesis at the sterol isomerase step

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Application of fluorescence in situ hybridization in genome analysis of the mouse

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Pharmacological analysis of sterol delta8-delta7 isomerase proteins with [3H]ifenprodil.

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7-Dehydrocholesterol down-regulates cholesterol biosynthesis in cultured Smith-Lemli-Opitz syndrome skin fibroblasts.

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2 June 2018

Regulation of hepatic cholesterol biosynthesis. Effects of a cytochrome P-450 inhibitor on the formation and metabolism of oxygenated sterol products of lanosterol

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2 June 2018

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2 June 2018

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27 November 2018

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27 November 2018

Cholesterol biosynthesis from lanosterol: regulation and purification of rat hepatic sterol 8-isomerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

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inferred from PubMed ID database lookup

Cholesterol biosynthesis from lanosterol: regulation and purification of rat hepatic sterol 14-reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of the ATP-sensitive K+ channel subunit Kir6.2 in mouse pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of tamoxifen on cholesterol synthesis in HepG2 cells and cultured rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical basis for a cholesterol-lowering activity of 2-[2"-(1",3"-dioxolane)]-2-methyl-4-(2'-oxo-1'-pyrrolidinyl)-6- nitro-2H-1-benzopyran (SKP-450), a novel antihypertensive agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal sterol metabolism in patients with Conradi-Hünermann-Happle syndrome and sporadic lethal chondrodysplasia punctata

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHILD syndrome caused by deficiency of 3beta-hydroxysteroid-delta8, delta7-isomerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concerning the Role of Lanosterol and Cycloartenol in Steroid Biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

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Microsomal enzymes of cholesterol biosynthesis from lanosterol. Solubilization and purification of steroid 8-isomerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate specificity of protein kinase C. Use of synthetic peptides corresponding to physiological sites as probes for substrate recognition requirements

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

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Mechanistic studies of lanosterol C-32 demethylation. Conditions which promote oxysterol intermediate accumulation during the demethylation process

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in the expression of cytochrome P-450 (b+e) gene in the rat after phenobarbitone administration

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen decreases serum cholesterol by inhibiting cholesterol synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen-induced decreases in total cholesterol with 2 weeks of treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/11171067

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/0264-6021:3530689

1 reference

Europe PubMed Central

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3 November 2019

1 reference

Europe PubMed Central

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3 November 2019

1 reference

Europe PubMed Central

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3 November 2019

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