Therapeutic targeting of the MEK/MAPK signal transduction module in acute myeloid leukemia (Q28354257)

2

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Z Estrov

3

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B Z Carter

4

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H Lapillonne

5

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D Harris

6

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M Konopleva

7

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S Zhao

8

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E Estey

9

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M Andreeff

Journal of Clinical Investigation

10

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language of work or name

English

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publication date

September 2001

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published in

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volume

108

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issue

6

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page(s)

851-9

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12 December 2020

Constitutive activation of extracellular signal-regulated kinase in human acute leukemias: combined role of activation of MEK, hyperexpression of extracellular signal-regulated kinase, and downregulation of a phosphatase, PAC1

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12 December 2020

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

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12 December 2020

Expression of Bcl-2-related genes in normal and AML progenitors: changes induced by chemotherapy and retinoic acid

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12 December 2020

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

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12 December 2020

Blockade of the extracellular signal-regulated kinase pathway induces marked G1 cell cycle arrest and apoptosis in tumor cells in which the pathway is constitutively activated: up-regulation of p27(Kip1)

1 reference

12 December 2020

Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway

1 reference

12 December 2020

Constitutive activation of mitogen-activated protein kinase pathway in acute leukemia cells

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12 December 2020

Identifiers

DOI

10.1172/JCI12807

1 reference

2321910

2321910

1 reference

1 reference

1 reference