The metal-responsive transcription factor-1 protein is elevated in human tumors (Q28386210)

1

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Khalid Amin

2

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Barbara G Sato

3

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Steven J Samuelsson

4

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Lidia Sambucetti

5

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Zishan A Haroon

6

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Keith Laderoute

7

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Brian J Murphy

Cancer Biology and Therapy

8

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language of work or name

English

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publication date

15 March 2010

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published in

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volume

9

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issue

6

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page(s)

469-76

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cites work

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Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

20 March 2017

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Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione

20 March 2017

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Regulation of metallothionein transcription by the metal-responsive transcription factor MTF-1: identification of signal transduction cascades that control metal-inducible transcription

20 March 2017

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Zinc metallothionein imported into liver mitochondria modulates respiration

20 March 2017

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Regulation of metallothionein gene expression by oxidative stress and metal ions

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Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

20 March 2017

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Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.

20 March 2017

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The transcription factor MTF-1 mediates metal regulation of the mouse ZnT1 gene

20 March 2017

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Chromium(VI) inhibits mouse metallothionein-I gene transcription by preventing the zinc-dependent formation of an MTF-1-p300 complex

20 March 2017

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Nuclear factor-kappaB in cancer development and progression

20 March 2017

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TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

7 April 2017

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Regulation of prion gene expression by transcription factors SP1 and metal transcription factor-1.

7 April 2017

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ZIP7-mediated intracellular zinc transport contributes to aberrant growth factor signaling in antihormone-resistant breast cancer Cells.

29 September 2017

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Regulation of ZIP and ZnT zinc transporters in zebrafish gill: zinc repression of ZIP10 transcription by an intronic MRE cluster

29 September 2017

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Zinc-induced formation of a coactivator complex containing the zinc-sensing transcription factor MTF-1, p300/CBP, and Sp1

29 September 2017

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NF-kappaB and cancer-identifying targets and mechanisms

29 September 2017

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Therapeutic significance of elevated tissue transglutaminase expression in pancreatic cancer.

29 September 2017

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Metallothionein induction by hypoxia involves cooperative interactions between metal-responsive transcription factor-1 and hypoxia-inducible transcription factor-1alpha

29 September 2017

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Understanding the mechanisms of zinc-sensing by metal-response element binding transcription factor-1 (MTF-1).

29 September 2017

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Metallothionein expression is suppressed in primary human hepatocellular carcinomas and is mediated through inactivation of CCAAT/enhancer binding protein alpha by phosphatidylinositol 3-kinase signaling cascade

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Development of novel therapeutic strategies that target HIF-1.

29 September 2017

1 reference

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The metal-responsive transcription factor-1 contributes to HIF-1 activation during hypoxic stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Regulation of malignant progression by the hypoxia-sensitive transcription factors HIF-1alpha and MTF-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Metal-responsive transcription factor-1 (MTF-1) selects different types of metal response elements at low vs. high zinc concentration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Loss of metal transcription factor-1 suppresses tumor growth through enhanced matrix deposition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Metallothioneins in human tumors and potential roles in carcinogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Antiapoptotic Effect and Inhibition of Ischemia/Reperfusion-Induced Myocardial Injury in Metallothionein-Overexpressing Transgenic Mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Zinc accumulation in N-methyl-N-nitrosourea-induced rat mammary tumors is accompanied by an altered expression of ZnT-1 and metallothionein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

TGF-beta signaling: positive and negative effects on tumorigenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Putting its fingers on stressful situations: the heavy metal-regulatory transcription factor MTF-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Inhibition of hypoxia/reoxygenation-induced apoptosis in metallothionein-overexpressing cardiomyocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Placenta growth factor gene expression is induced by hypoxia in fibroblasts: a central role for metal transcription factor-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Target gene search for the metal-responsive transcription factor MTF-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Characterization of the mouse gene for the heavy metal-responsive transcription factor MTF-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Metallothionein in radiation exposure: its induction and protective role

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Activation of metallothionein gene expression by hypoxia involves metal response elements and metal transcription factor-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Nitric oxide-induced nuclear translocation of the metal responsive transcription factor, MTF-1 is mediated by zinc release from metallothionein

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Elevated metallothionein (MT) expression in invasive ductal breast cancers predicts tamoxifen resistance.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxification in the adult liver

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Zinc-metallothionein protects from DNA damage induced by radiation better than glutathione and copper- or cadmium-metallothioneins

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Metallothionein 2A expression is associated with cell proliferation in breast cancer

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

The heavy metal-responsive transcription factor-1 (MTF-1) is not required for neural differentiation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3039317

Role of metal-responsive transcription factor-1 (MTF-1) in EGF-dependent DNA synthesis in primary hepatocytes

27 November 2018

1 reference

12 December 2020

Protection from radiation-induced DNA single-strand breaks by induction of nuclear metallothionein

1 reference

12 December 2020

Ribosomal protein S25 mRNA partners with MTF-1 and La to provide a p53-mediated mechanism for survival or death

1 reference

12 December 2020

MRE-binding transcription factor-1 is activated during endotoxemia: a central role for metallothionein

1 reference

12 December 2020

Metallothionein as a prognostic biomarker in breast cancer

1 reference

12 December 2020

Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer xenografts

1 reference

12 December 2020

Identifiers

DOI

10.4161/CBT.9.6.10979

1 reference

release_uubat22xj5bbffh3yma73dib5m

Fatcat ID

0 references

1 reference

1 reference

PubMed publication ID

20087061

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