Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease (Q28391826)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878270%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease (English)

1 reference

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5 March 2020

1 reference

1

1 reference

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5 March 2020

Jennifer E Lee

2

1 reference

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5 March 2020

Candice M Brown

5

1 reference

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5 March 2020

Michael P Vitek

8

1 reference

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5 March 2020

Michael Dee Gunn

9

1 reference

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5 March 2020

Carol A. Colton

10

1 reference

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5 March 2020

6

Andrew N Hoofnagle

1 reference

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5 March 2020

author name string

Joan G Wilson

3

1 reference

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5 March 2020

Angela L Everhart

4

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5 March 2020

Marilyn Jansen

7

1 reference

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5 March 2020

language of work or name

English

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publication date

1 April 2015

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5 March 2020

published in

Journal of Neuroscience

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5 March 2020

volume

35

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5 March 2020

page(s)

5969-5982

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5 March 2020

issue

15

1 reference

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miRNA-939 regulates human inducible nitric oxide synthase posttranscriptional gene expression in human hepatocytes

5 March 2020

cites work

1 reference

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Arginases and arginine deficiency syndromes

20 March 2017

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Arginase activities and global arginine bioavailability in wild-type and ApoE-deficient mice: responses to high fat and high cholesterol diets

20 March 2017

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Neuroinflammation – An Early Event in Both the History and Pathogenesis of Alzheimer’s Disease

20 March 2017

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Myeloid-derived suppressor cells as regulators of the immune system

20 March 2017

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Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection

20 March 2017

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CNS immune privilege: hiding in plain sight

20 March 2017

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A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease

20 March 2017

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Quantitative PCR for detection of the OT-1 transgene

20 March 2017

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Of mice and not men: differences between mouse and human immunology

20 March 2017

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

20 March 2017

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Dispensable and indispensable amino acids for humans

20 March 2017

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Neuron-specific expression of cationic amino acid transporter 3 in the adult rat brain

20 March 2017

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Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor

20 March 2017

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The novel activated microglia/macrophage WAP domain protein, AMWAP, acts as a counter-regulator of proinflammatory response

20 March 2017

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Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development

20 March 2017

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Gng12 is a novel negative regulator of LPS-induced inflammation in the microglial cell line BV-2

20 March 2017

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Genome-wide association study of Alzheimer's disease

20 March 2017

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Regulation of immune responses by L-arginine metabolism

7 April 2017

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Osteopontin shapes immunosuppression in the metastatic niche

7 April 2017

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mNos2 deletion and human NOS2 replacement in Alzheimer disease models

29 September 2017

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Programmed death 1 deficiency induces the polarization of macrophages/microglia to the M1 phenotype after spinal cord injury in mice

29 September 2017

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Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization

29 September 2017

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Loss of serum IGF-I input to the brain as an early biomarker of disease onset in Alzheimer mice.

29 September 2017

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Understanding the neurobiology of CD200 and the CD200 receptor: a therapeutic target for controlling inflammation in human brains?

29 September 2017

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The microglial sensome revealed by direct RNA sequencing

29 September 2017

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Type I IFNs downregulate myeloid cell IFN-γ receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription.

29 September 2017

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Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits

29 September 2017

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Metabolic profiling of Alzheimer's disease brains

29 September 2017

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CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

29 September 2017

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Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease

29 September 2017

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Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation

29 September 2017

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Systemic immune system alterations in early stages of Alzheimer's disease

29 September 2017

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Metabolic stress in autophagy and cell death pathways

29 September 2017

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The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes

29 September 2017

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Diverse inflammatory responses in transgenic mouse models of Alzheimer's disease and the effect of immunotherapy on these responses

29 September 2017

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Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence

29 September 2017

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Tumor-infiltrating programmed death receptor-1+ dendritic cells mediate immune suppression in ovarian cancer

29 September 2017

1 reference

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Simultaneous determination of 6 L-arginine metabolites in human and mouse plasma by using hydrophilic-interaction chromatography and electrospray tandem mass spectrometry

29 September 2017

1 reference

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Nitric oxide and redox mechanisms in the immune response

29 September 2017

1 reference

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The myeloid cells of the central nervous system parenchyma

29 September 2017

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Is the urea cycle involved in Alzheimer's disease?

29 September 2017

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Macrophages and immunologic inflammation of the kidney

29 September 2017

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Diminished global arginine bioavailability and increased arginine catabolism as metabolic profile of increased cardiovascular risk

29 September 2017

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Inflammation in Alzheimer's disease: amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors

29 September 2017

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Arginase-1-expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosis

29 September 2017

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The effects of NOS2 gene deletion on mice expressing mutated human AbetaPP.

29 September 2017

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Arginine metabolism and nutrition in growth, health and disease

29 September 2017

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Microglia: gatekeepers of central nervous system immunology.

29 September 2017

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Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells

29 September 2017

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Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid

29 September 2017

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The value of incomplete mouse models of Alzheimer's disease

29 September 2017

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Creating immune privilege: active local suppression that benefits friends, but protects foes.

29 September 2017

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Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways

29 September 2017

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Arginine metabolism: boundaries of our knowledge

29 September 2017

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Structure and function of cationic amino acid transporters (CATs).

29 September 2017

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Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD

29 September 2017

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Structure of the blood-brain barrier and its role in the transport of amino acids

29 September 2017

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Investigations with cultured human microglia on pathogenic mechanisms of Alzheimer's disease and other neurodegenerative diseases

29 September 2017

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Toll-like receptor 2 stimulation decreases IFN-gamma receptor expression in mouse RAW264.7 macrophages.

29 September 2017

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Glia and their cytokines in progression of neurodegeneration

29 September 2017

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Disrupted spermine homeostasis: a novel mechanism in polyglutamine-mediated aggregation and cell death.

29 September 2017

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Thirty Years of Polyamine-Related Approaches to Cancer Therapy. Retrospect and Prospect. Part 2. Structural Analogues and Derivatives

29 September 2017

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Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide

29 September 2017

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Adaptation of plasma membrane amino acid transport mechanisms to physiological demands.

29 September 2017

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Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-kappa B.

29 September 2017

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The gp49A gene has extensive sequence conservation with the gp49B gene and provides gp49A protein, a unique member of a large family of activating and inhibitory receptors of the immunoglobulin superfamily

29 September 2017

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Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization

29 September 2017

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Protective roles of nitric oxide and testosterone in endotoxemia: evidence from NOS-2-deficient mice

29 September 2017

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Species differences in the generation of reactive oxygen species by microglia

29 September 2017

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Phase I trial and pharmacokinetic studies of alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis

29 September 2017

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Difluoromethylornithine for arseno-resistant Trypanosoma brucei gambiense sleeping sickness

29 September 2017

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Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques

29 September 2017

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Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma

29 September 2017

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Progression of amyloid pathology to Alzheimer's disease pathology in an amyloid precursor protein transgenic mouse model by removal of nitric oxide synthase 2

2 June 2018

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Alpha-difluoromethylornithine (DFMO) as a potent arginase activity inhibitor in human colon carcinoma cells

2 June 2018

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Molecular biology of nitric oxide synthases

2 June 2018

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Modulation of nitric oxide production in human macrophages by apolipoprotein-E and amyloid-beta peptide.

2 June 2018

1 reference

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Direct ex vivo flow cytometric analysis of human microglial cell CD4 expression: examination of central nervous system biopsy specimens from HIV-seropositive patients and patients with other neurological disease.

2 June 2018

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Adaptive regulation of the cationic amino acid transporter-1 (Cat-1) in Fao cells

2 June 2018

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Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia.

2 June 2018

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Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages.

2 June 2018

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Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Role of microglia in plaque formation in senile dementia of the Alzheimer type. An immunohistochemical study.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Brain microglia constitutively express beta-2 integrins.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Altered arginine metabolism in Alzheimer's disease brains.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Classical activation of microglia in CD200-deficient mice is a consequence of blood brain barrier permeability and infiltration of peripheral cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

APBB2 genetic polymorphisms are associated with severe cognitive impairment in centenarians.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Alzheimer's disease: amino acid levels and brain metabolic status.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

CC chemokine receptor 2 deficiency aggravates cognitive impairments and amyloid pathology in a transgenic mouse model of Alzheimer's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Osteopontin is increased in the cerebrospinal fluid of patients with Alzheimer's disease and its levels correlate with cognitive decline.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Nutrient deprivation induces neuronal autophagy and implicates reduced insulin signaling in neuroprotective autophagy activation

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Microglia can be induced by IFN-gamma or IL-4 to express neural or dendritic-like markers.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Two-day radial-arm water maze learning and memory task; robust resolution of amyloid-related memory deficits in transgenic mice.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

An active transport system in the blood-brain barrier may reduce levodopa availability

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Human LAT1 single nucleotide polymorphism N230K does not alter phenylalanine transport

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Rapid high-throughput assay for the measurement of amino acids from microdialysates and brain tissue using monolithic C18-bonded reversed-phase columns

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Early-onset and robust cerebral microvascular accumulation of amyloid beta-protein in transgenic mice expressing low levels of a vasculotropic Dutch/Iowa mutant form of amyloid beta-protein precursor

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

CCR1 is an early and specific marker of Alzheimer's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Expression of arginase isozymes in mouse brain

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Dietary polyamines are essential luminal growth factors for small intestinal and colonic mucosal growth and development

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Reactive microglia express class I and class II major histocompatibility complex antigens in Alzheimer's disease.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4397598

Effect of diaminobutene and diaminopropane on diet-stimulated polyamine synthesis and cell proliferation in rat liver

27 November 2018

1 reference

12 December 2020

Maturation of villus and crypt cell functions in rat small intestine. Role of dietary polyamines

1 reference

12 December 2020

Rods and cones in the mouse retina. II. Autoradiographic analysis of cell generation using tritiated thymidine

1 reference

12 December 2020

Effects of the new arginase inhibitor N(omega)-hydroxy-nor-L-arginine on NO synthase activity in murine macrophages

1 reference

12 December 2020

CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase

1 reference

12 December 2020

Physiological role of autophagy as an intracellular recycling system: with an emphasis on nutrient metabolism

1 reference

12 December 2020

10.1523/JNEUROSCI.4668-14.2015

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878270%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878270%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25878270%20AND%20SRC:MED&resulttype=core&format=json