Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS (Q28393678)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19914377%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS (English)

1 reference

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amyotrophic lateral sclerosis

12 February 2020

main subject

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0 references

2

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12 February 2020

author name string

Ana G Barbeito

1

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12 February 2020

Marcelo R Vargas

3

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12 February 2020

Mariana Pehar

4

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12 February 2020

Nelly Mañay

5

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12 February 2020

Joseph S Beckman

6

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12 February 2020

Luis Barbeito

7

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12 February 2020

Patricia Cassina

8

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12 February 2020

language of work or name

English

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publication date

13 November 2009

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12 February 2020

published in

Neurobiology of Disease

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12 February 2020

volume

37

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12 February 2020

issue

3

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12 February 2020

page(s)

574-580

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describes a project that uses

12 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2824063/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

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Onset and progression in inherited ALS determined by motor neurons and microglia

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Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

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Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants

7 April 2017

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Very low lead exposures and children's neurodevelopment

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Vascular endothelial growth factor overexpression delays neurodegeneration and prolongs survival in amyotrophic lateral sclerosis mice

29 September 2017

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Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

29 September 2017

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Constitutive and inducible expression and regulation of vascular endothelial growth factor

29 September 2017

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Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene

29 September 2017

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Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

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Astroglia as metal depots: molecular mechanisms for metal accumulation, storage and release

29 September 2017

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Cell culture models for lead toxicity in neuronal and glial cells

29 September 2017

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Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis

29 September 2017

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Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase.

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Lead exposure as a risk factor for Amyotrophic Lateral Sclerosis

27 November 2018

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Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis

27 November 2018

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Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival.

27 November 2018

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Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

27 November 2018

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Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration

27 November 2018

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Differential induction of heme oxygenase and other stress proteins in cultured hippocampal astrocytes and neurons by inorganic lead

27 November 2018

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VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

27 November 2018

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VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death

27 November 2018

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Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis

27 November 2018

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Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

27 November 2018

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A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis

27 November 2018

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12 December 2020

Post natal antioxidant enzyme activity of rat brain regions during developmental lead exposure

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12 December 2020

VEGF reduces astrogliosis and preserves neuromuscular junctions in ALS transgenic mice

1 reference

12 December 2020

Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS)

1 reference

12 December 2020

Induction of vascular endothelial growth factor in human astrocytes by lead. Involvement of a protein kinase C/activator protein-1 complex-dependent and hypoxia-inducible factor 1-independent signaling pathway

1 reference

12 December 2020

10.1016/J.NBD.2009.11.007

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19914377%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19914377%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

19914377

1 reference