Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene (Q28469173)

Timothy Barrett

4

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Ewan Pearson

Ewan R Pearson

1

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Sian Ellard

Sian Ellard

7

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Andrew Tym Hattersley

9

Andrew T Hattersley

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author name string

Sylvia F Boj

2

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Anna M Steele

3

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Karen Stals

5

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Julian P Shield

Creative Commons Attribution 4.0 International

6

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language of work or name

English

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publication date

April 2007

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published in

PLOS MEDICINE

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volume

4

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page(s)

e118

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issue

4

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copyright license

start time

3 April 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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A conditional model reveals that induction of hepatocyte nuclear factor-1alpha in Hnf1alpha-null mutant beta-cells can activate silenced genes postnatally, whereas overexpression is deleterious

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Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12.

2 June 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages

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12 December 2020

Beta-cell proliferation and apoptosis in the developing normal human pancreas and in hyperinsulinism of infancy

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12 December 2020

Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion

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12 December 2020

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

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10.1371/JOURNAL.PMED.0040118

Identifiers

DOI

1 reference

4529061

4529061

1 reference

1 reference

1 reference