V3 loop truncations in HIV-1 envelope impart resistance to coreceptor inhibitors and enhanced sensitivity to neutralizing antibodies (Q28469283)

12

James A Hoxie

0 references

Beth S Haggarty

3

Beth Haggarty

0 references

Meg M Laakso

1

Meg M Laakso

0 references

Mark Biscone

6

Mark Biscone

0 references

author name string

Fang-Hua Lee

2

0 references

Caroline Agrawal

4

0 references

Katrina M Nolan

5

0 references

Josephine Romano

7

0 references

Andrea P O Jordan

8

0 references

George J Leslie

9

0 references

Eric G Meissner

10

0 references

Lishan Su

Creative Commons Attribution 4.0 International

11

0 references

language of work or name

English

0 references

publication date

24 August 2007

0 references

published in

PLOS Pathogens

0 references

volume

3

0 references

issue

8

0 references

page(s)

e117

0 references

copyright license

start time

24 August 2007

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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7 April 2017

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7 April 2017

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Fusion-induced apoptosis contributes to thymocyte depletion by a pathogenic human immunodeficiency virus type 1 envelope in the human thymus

29 September 2017

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Functional impact of HIV coreceptor-binding site mutations

29 September 2017

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The V1, V2, and V3 regions of the human immunodeficiency virus type 1 envelope differentially affect the viral phenotype in an isolate-dependent manner

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29 September 2017

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Generation and properties of a human immunodeficiency virus type 1 isolate resistant to the small molecule CCR5 inhibitor, SCH-417690 (SCH-D).

29 September 2017

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Thymic pathogenicity of an HIV-1 envelope is associated with increased CXCR4 binding efficiency and V5-gp41-dependent activity, but not V1/V2-associated CD4 binding efficiency and viral entry

29 September 2017

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Antigenic conservation and immunogenicity of the HIV coreceptor binding site

29 September 2017

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Enfuvirtide resistance mutations: impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity, and virus neutralization

29 September 2017

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Kinetic factors control efficiencies of cell entry, efficacies of entry inhibitors, and mechanisms of adaptation of human immunodeficiency virus

29 September 2017

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29 September 2017

V3: HIV's switch-hitter

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The CCR5 receptor-based mechanism of action of 873140, a potent allosteric noncompetitive HIV entry inhibitor

29 September 2017

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Characterization of a thymus-tropic HIV-1 isolate from a rapid progressor: role of the envelope

29 September 2017

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Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity

29 September 2017

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Selective modification of variable loops alters tropism and enhances immunogenicity of human immunodeficiency virus type 1 envelope

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics

29 September 2017

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The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor

29 September 2017

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CD4 independence of simian immunodeficiency virus Envs is associated with macrophage tropism, neutralization sensitivity, and attenuated pathogenicity

29 September 2017

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A replication-competent, neutralization-sensitive variant of simian immunodeficiency virus lacking 100 amino acids of envelope

29 September 2017

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Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

29 September 2017

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Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein

29 September 2017

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Increased neutralization sensitivity of CD4-independent human immunodeficiency virus variants

29 September 2017

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Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding

29 September 2017

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Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120

29 September 2017

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Human immunodeficiency virus type 1 pathogenesis in SCID-hu mice correlates with syncytium-inducing phenotype and viral replication

29 September 2017

1 reference

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Role of CXCR4 in cell-cell fusion and infection of monocyte-derived macrophages by primary human immunodeficiency virus type 1 (HIV-1) strains: two distinct mechanisms of HIV-1 dual tropism.

29 September 2017

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Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein

29 September 2017

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Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function

29 September 2017

1 reference

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An envelope modification that renders a primary, neutralization-resistant clade B human immunodeficiency virus type 1 isolate highly susceptible to neutralization by sera from other clades.

29 September 2017

1 reference

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Infection with dual-tropic human immunodeficiency virus type 1 variants associated with rapid total T cell decline and disease progression in injection drug users

29 September 2017

1 reference

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Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein

29 September 2017

1 reference

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Cell-cell fusion assay to study role of chemokine receptors in human immunodeficiency virus type 1 entry

29 September 2017

1 reference

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Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding

29 September 2017

1 reference

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Functional and immunologic characterization of human immunodeficiency virus type 1 envelope glycoproteins containing deletions of the major variable regions

29 September 2017

1 reference

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Biological, molecular, and structural analysis of a cytopathic variant from a molecularly cloned simian immunodeficiency virus

29 September 2017

1 reference

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Syncytium-inducing and non-syncytium-inducing capacity of human immunodeficiency virus type 1 subtypes other than B: phenotypic and genotypic characteristics. WHO Network for HIV Isolation and Characterization

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Sequence diversity of V1 and V2 domains of gp120 from human immunodeficiency virus type 1: lack of correlation with viral phenotype.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Isolation and characterization of a syncytium-inducing, macrophage/T-cell line-tropic human immunodeficiency virus type 1 isolate that readily infects chimpanzee cells in vitro and in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Correlation between genetic and biological properties of biologically cloned HIV type 1 viruses representing subtypes A, B, and D.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Distinct modes of human immunodeficiency virus type 1 proviral latency revealed by superinfection of nonproductively infected cell lines with recombinant luciferase-encoding viruses.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Principal neutralizing domain of the human immunodeficiency virus type 1 envelope protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Antibodies that inhibit fusion of human immunodeficiency virus-infected cells bind a 24-amino acid sequence of the viral envelope, gp120

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1.

29 September 2017

1 reference

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Human immunodeficiency virus type 1 clones chimeric for the envelope V3 domain differ in syncytium formation and replication capacity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1950945

Regulated expression of foreign genes in vaccinia virus under the control of bacteriophage T7 RNA polymerase and the Escherichia coli lac repressor

29 September 2017

1 reference

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Minimal requirements for the human immunodeficiency virus type 1 V3 domain to support the syncytium-inducing phenotype: analysis by single amino acid substitution

29 September 2017

1 reference

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Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region

29 September 2017

1 reference

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Investigation of population diversity of human immunodeficiency virus type 1 in vivo by nucleotide sequencing and length polymorphism analysis of the V1/V2 hypervariable region of env.

29 September 2017

1 reference

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Studies on the role of the V3 loop in human immunodeficiency virus type 1 envelope glycoprotein function

2 June 2018

1 reference

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An anti-CCR5 monoclonal antibody and small molecule CCR5 antagonists synergize by inhibiting different stages of human immunodeficiency virus type 1 entry

2 June 2018

1 reference

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HIV vaccine design and the neutralizing antibody problem

27 November 2018

1 reference

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Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

27 November 2018

1 reference

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10.1371/JOURNAL.PPAT.0030117

27 November 2018

Identifiers

DOI

1 reference

release_daeqtdmuone2xdeodmkt5ycvji

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/daeqtdmuone2xdeodmkt5ycvji

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

1 reference

PubMed publication ID

17722977

1 reference