Pharmacological inhibition of microsomal prostaglandin E synthase-1 suppresses epidermal growth factor receptor-mediated tumor growth and angiogenesis (Q28481397)

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English	Pharmacological inhibition of microsomal prostaglandin E synthase-1 suppresses epidermal growth factor receptor-mediated tumor growth and angiogenesis	scientific article

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8 February 2020

Pharmacological inhibition of microsomal prostaglandin E synthase-1 suppresses epidermal growth factor receptor-mediated tumor growth and angiogenesis (English)

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8 February 2020

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prostaglandin E2

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Federica Finetti

1

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8 February 2020

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8 February 2020

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8 February 2020

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Elena Bocci

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8 February 2020

Isabella Coletta

4

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8 February 2020

Lorenzo Polenzani

5

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8 February 2020

Giorgina Mangano

6

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8 February 2020

Maria Alessandra Alisi

7

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8 February 2020

Nicola Cazzolla

8

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8 February 2020

Antonio Giachetti

9

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8 February 2020

Marina Ziche

10

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8 February 2020

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18 July 2012

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8 February 2020

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8 February 2020

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8 February 2020

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8 February 2020

e40576

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8 February 2020

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Creative Commons Attribution 4.0 International

18 July 2012

1 reference

April 2022 Public Data File from Crossref

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0 references

Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward

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19 March 2017

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

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7 April 2017

EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity

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29 September 2017

Microsomal prostaglandin E synthase-1 inhibits PTEN and promotes experimental cholangiocarcinogenesis and tumor progression

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29 September 2017

Structure-based discovery of inhibitors of microsomal prostaglandin E2 synthase-1, 5-lipoxygenase and 5-lipoxygenase-activating protein: promising hits for the development of new anti-inflammatory agents.

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29 September 2017

Inhibition of microsomal prostaglandin E2 synthase-1 as a molecular basis for the anti-inflammatory actions of boswellic acids from frankincense

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29 September 2017

Inhibition of hypoxia inducible factor-1alpha by dihydroxyphenylethanol, a product from olive oil, blocks microsomal prostaglandin-E synthase-1/vascular endothelial growth factor expression and reduces tumor angiogenesis.

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29 September 2017

Microsomal prostaglandin E synthase-1 and 5-lipoxygenase: potential drug targets in cancer

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29 September 2017

The role of COX-2 in intestinal inflammation and colorectal cancer

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29 September 2017

Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro

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29 September 2017

Pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399882

29 September 2017

MF63 [2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)-isophthalonitrile], a selective microsomal prostaglandin E synthase-1 inhibitor, relieves pyresis and pain in preclinical models of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399882

29 September 2017

Membrane prostaglandin E synthase-1: a novel therapeutic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399882

29 September 2017

EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399882

29 September 2017

Role of prostaglandin E2-dependent angiogenic switch in cyclooxygenase 2-induced breast cancer progression

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29 September 2017

Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478.

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29 September 2017

Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis

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29 September 2017

Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy

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29 September 2017

COX-2: a target for colon cancer prevention

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29 September 2017

Inducible prostaglandin E synthase is overexpressed in non-small cell lung cancer

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29 September 2017

Prostaglandin E2 regulates angiogenesis via activation of fibroblast growth factor receptor-1.

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2 June 2018

Regulation of 5-lipoxygenase and 5-lipoxygenase-activating protein expression in HL-60 cells

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2 June 2018

Cyclooxygenase-2 and microsomal prostaglandin E synthase-1 are overexpressed in squamous cell carcinoma of the penis

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21 January 2018

Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis

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21 January 2018

Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptor

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Distinction of microsomal prostaglandin E synthase-1 (mPGES-1) inhibition from cyclooxygenase-2 inhibition in cells using a novel, selective mPGES-1 inhibitor

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Abeta peptides accelerate the senescence of endothelial cells in vitro and in vivo, impairing angiogenesis.

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Coordinate up- and down-regulation of glutathione-dependent prostaglandin E synthase and cyclooxygenase-2 in A549 cells. Inhibition by NS-398 and leukotriene C4

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Role of prostaglandin E1 and copper in angiogenesis

1 reference

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12 December 2020

based on heuristic

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10.1371/JOURNAL.PONE.0040576

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8 February 2020

2012PLoSO...740576F

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Consolidated OpenCitations Corpus – April 2017

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8 February 2020

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