Characterization of isoenzyme-selective inhibitors of human sphingosine kinases (Q28483643)

1

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Yuri K Peterson

2

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Ryan A Smith

3

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Charles D Smith

Creative Commons Attribution 4.0 International

4

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language of work or name

English

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publication date

2012

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published in

PLOS One

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volume

7

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issue

9

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page(s)

e44543

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copyright license

start time

10 September 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3438171/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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The Sphingosine Kinase 1 Inhibitor 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole Induces Proteasomal Degradation of Sphingosine Kinase 1 in Mammalian Cells

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Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons

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29 September 2017

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29 September 2017

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Sphingosine and its methylated derivative N,N-dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines

29 September 2017

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N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets

29 September 2017

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29 September 2017

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Sphingosine-1-phosphate, a novel lipid, involved in cellular proliferation

29 September 2017

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Cell membrane signaling as target in cancer therapy: inhibitory effect of N,N-dimethyl and N,N,N-trimethyl sphingosine derivatives on in vitro and in vivo growth of human tumor cells in nude mice

29 September 2017

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SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism

29 September 2017

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Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis

2 June 2018

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Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase

2 June 2018

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N,N-Dimethylsphingosine is a potent competitive inhibitor of sphingosine kinase but not of protein kinase C: modulation of cellular levels of sphingosine 1-phosphate and ceramide.

2 June 2018

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Consensus sequences for ATP-binding sites in protein kinases do not apply to diacylglycerol kinases

2 June 2018

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Synthesis and evaluation of sphingoid analogs as inhibitors of sphingosine kinases

2 June 2018

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Immune cell regulation and cardiovascular effects of sphingosine 1-phosphate receptor agonists in rodents are mediated via distinct receptor subtypes.

27 November 2018

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Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis

27 November 2018

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Effect of chemically well-defined sphingosine and its N-methyl derivatives on protein kinase C and src kinase activities

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22970244