Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata (Q28483785)

Ying-Lien Chen

6

0 references

Susan M. Poutanen

Susan M Poutanen

7

0 references

Leah E Cowen

Leah E Cowen

10

0 references

Joseph Heitman

9

Joseph Heitman

0 references

author name string

Sheena D Singh-Babak

1

0 references

Tomas Babak

2

0 references

Jessica A Hill

4

0 references

Jinglin Lucy Xie

5

0 references

Robert P Rennie

Creative Commons Attribution 4.0 International

8

0 references

language of work or name

English

0 references

publication date

2012

0 references

published in

PLOS Pathogens

0 references

volume

8

0 references

issue

5

0 references

page(s)

e1002718

0 references

copyright license

start time

17 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Fungicidal synergism of fluconazole and cyclosporine in Candida albicans is not dependent on multidrug efflux transporters encoded by the CDR1, CDR2, CaMDR1, and FLU1 genes.

29 September 2017

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29 September 2017

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In vitro activity of caspofungin (MK-0991) against Candida albicans clinical isolates displaying different mechanisms of azole resistance

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29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Evolution of drug resistance in experimental populations of Candida albicans.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Calcineurin. Structure, function, and inhibition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Temperature-induced expression of yeast FKS2 is under the dual control of protein kinase C and calcineurin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

CDC55, a Saccharomyces cerevisiae gene involved in cellular morphogenesis: identification, characterization, and homology to the B subunit of mammalian type 2A protein phosphatase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Resistance to echinocandins comes at a cost: the impact of FKS1 hotspot mutations on Candida albicans fitness and virulence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

An A643V amino acid substitution in Upc2p contributes to azole resistance in well-characterized clinical isolates of Candida albicans.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

FKS Mutations and Elevated Echinocandin MIC Values among Candida glabrata Isolates from U.S. Population-Based Surveillance

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Hsp90 orchestrates temperature-dependent Candida albicans morphogenesis via Ras1-PKA signaling

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Correlating echinocandin MIC and kinetic inhibition of fks1 mutant glucan synthases for Candida albicans: implications for interpretive breakpoints

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

MNL1 regulates weak acid-induced stress responses of the fungal pathogen Candida albicans

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Candida albicans and Candida glabrata clinical isolates exhibiting reduced echinocandin susceptibility

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Aneuploidy and isochromosome formation in drug-resistant Candida albicans

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Assessing resistance to the echinocandin antifungal drug caspofungin in Candida albicans by profiling mutations in FKS1

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Population Biology, Evolution, and Infectious Disease: Convergence and Synthesis

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

The epidemiology and attributable outcomes of candidemia in adults and children hospitalized in the United States: a propensity analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Genomic polymorphism in the population of Candida glabrata: Gene copy-number variation and chromosomal translocations

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

An isochromosome confers drug resistance in vivo by amplification of two genes, ERG11 and TAC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Role of the Slt2 mitogen-activated protein kinase pathway in cell wall integrity and virulence in Candida glabrata

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Diverse cellular functions of the Hsp90 molecular chaperone uncovered using systems approaches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

The role of nutrient regulation and the Gpa2 protein in the mating pheromone response of C. albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

The yeast ORF YDL202w codes for the mitochondrial ribosomal protein YmL11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Escaping an evolutionary lobster trap: drug resistance and compensatory mutation in a fluctuating environment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Modulation of fluconazole sensitivity by the interaction of mitochondria and erg3p in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Biological consequences of petite mutations in Candida glabrata

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Reversal of antifungal resistance mediated by ABC efflux pumps from Candida albicans functionally expressed in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Synergistic effect of calcineurin inhibitors and fluconazole against Candida albicans biofilms

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Plasmodium falciparum calcineurin and its association with heat shock protein 90: mechanisms for the antimalarial activity of cyclosporin A and synergism with geldanamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

Cdc6p establishes and maintains a state of replication competence during G1 phase.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3355103

Caspofungin activity against clinical isolates of azole cross-resistant Candida glabrata overexpressing efflux pump genes

27 November 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002718

A role for Saccharomyces cerevisiae fatty acid activation protein 4 in regulating protein N-myristoylation during entry into stationary phase

21 January 2018

1 reference

12 December 2020

Calcineurin is required for Leishmania major stress response pathways and for virulence in the mammalian host

1 reference

12 December 2020

In-vivo selection of an azole-resistant petite mutant of Candida glabrata

1 reference

12 December 2020

Expression of the yeast glycogen phosphorylase gene is regulated by stress-response elements and by the HOG MAP kinase pathway

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1002718

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

22615574

1 reference