SKLB023 blocks joint inflammation and cartilage destruction in arthritis models via suppression of nuclear factor-kappa B activation in macrophage (Q28486238)

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English	SKLB023 blocks joint inflammation and cartilage destruction in arthritis models via suppression of nuclear factor-kappa B activation in macrophage	scientific article

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scholarly article

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SKLB023 blocks joint inflammation and cartilage destruction in arthritis models via suppression of nuclear factor-kappa B activation in macrophage (English)

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Liang Ma

2

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author name string

Caifeng Xie

1

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Juan Liu

3

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Xiuxia Li

4

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Heying Pei

5

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Mingli Xiang

6

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Lijuan Chen

7

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language of work or name

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publication date

2013

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8

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2

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e56349

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copyright license

Creative Commons Attribution 4.0 International

19 February 2013

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April 2022 Public Data File from Crossref

copyright status

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Macrophages in rheumatoid arthritis

1 reference

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19 March 2017

The NF-kappa B and I kappa B proteins: new discoveries and insights

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19 March 2017

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

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19 March 2017

Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases

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7 April 2017

Evolving concepts of rheumatoid arthritis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

7 April 2017

NF-kappaB: a key role in inflammatory diseases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

7 April 2017

Are we moving in the right direction with osteoarthritis drug discovery?

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29 September 2017

Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Synthesis and biological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives for the treatment of inflammatory diseases

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29 September 2017

Inhibition of NF-κB signaling as a strategy in disease therapy

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29 September 2017

Monocyte scintigraphy in rheumatoid arthritis: the dynamics of monocyte migration in immune-mediated inflammatory disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Treatment of rheumatoid arthritis: state of the art 2009.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Signalling, inflammation and arthritis: NF-kappaB and its relevance to arthritis and inflammation.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

MAPKs and their relevance to arthritis and inflammation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Cells of the synovium in rheumatoid arthritis. Macrophages

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Utility of animal models for identification of potential therapeutics for rheumatoid arthritis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

The pathogenesis of rheumatoid arthritis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Treatment of rheumatoid arthritis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

New drugs for rheumatoid arthritis

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29 September 2017

Signal transduction networks in rheumatoid arthritis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

The pathogenesis of rheumatoid arthritis: pivotal cytokines involved in bone degradation and inflammation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Newer immunosuppressive drugs: their potential role in rheumatoid arthritis therapy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Cytokine pathways and joint inflammation in rheumatoid arthritis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Effect of interleukin 17 on proteoglycan degradation in murine knee joints

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29 September 2017

Nitric oxide synthase and cyclooxygenases: distribution, regulation, and intervention in arthritis.

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29 September 2017

Defining therapeutic targets by using adenovirus: blocking NF-kappaB inhibits both inflammatory and destructive mechanisms in rheumatoid synovium but spares anti-inflammatory mediators

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29 September 2017

Signal transduction and transcription factors in rheumatic disease

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29 September 2017

NF-kappaB activation provides the potential link between inflammation and hyperplasia in the arthritic joint

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3576337

29 September 2017

Antigen-induced arthritis in mice. I. Induction of arthritis in various strains of mice.

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2 June 2018

Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation

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21 January 2018

Nramp1 functionality increases inducible nitric oxide synthase transcription via stimulation of IFN regulatory factor 1 expression

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21 January 2018

Human RPE-monocyte co-culture induces chemokine gene expression through activation of MAPK and NIK cascade

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21 January 2018

Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue

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21 January 2018

Animal models of rheumatoid arthritis

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https://pubmed.ncbi.nlm.nih.gov/23431370

12 December 2020

based on heuristic

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Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the synovial cell infiltrate in early rheumatoid synovial tissue in relation to local disease activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/23431370

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0056349

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2013PLoSO...856349X

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