Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment (Q28506526)

24 January 2017

title

Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment (English)

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FMS-like tyrosine kinase 3

24 January 2017

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GOA release 2020-03-11

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GOA release 2020-03-11

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3

Lynn M. Corcoran

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24 January 2017

Melissa L. Holmes

1

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24 January 2017

Sebastian Carotta

series ordinal

2

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24 January 2017

Stephen L. Nutt

series ordinal

4

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24 January 2017

publication date

15 April 2006

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24 January 2017

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24 January 2017

volume

20

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24 January 2017

issue

8

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24 January 2017

page(s)

933–938

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Key role of flt3 ligand in regulation of the common lymphoid progenitor but not in maintenance of the hematopoietic stem cell pool

24 January 2017

cites work

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Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors

19 March 2017

1 reference

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Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472301

Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472301

The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP

19 March 2017

1 reference

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A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells

19 March 2017

1 reference

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Contingent gene regulatory networks and B cell fate specification

7 April 2017

1 reference

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Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro

29 September 2017

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Transcriptional control of early B cell development

29 September 2017

1 reference

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The early progenitors of mouse dendritic cells and plasmacytoid predendritic cells are within the bone marrow hemopoietic precursors expressing Flt3

29 September 2017

1 reference

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PU.1 regulates expression of the interleukin-7 receptor in lymphoid progenitors

29 September 2017

1 reference

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Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain

29 September 2017

1 reference

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Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells

29 September 2017

1 reference

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Defects in hemopoietic stem cell activity in Ikaros mutant mice

29 September 2017

1 reference

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Coordinate regulation of B cell differentiation by the transcription factors EBF and E2A.

29 September 2017

1 reference

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Dendritic cell development in culture from thymic precursor cells in the absence of granulocyte/macrophage colony-stimulating factor

29 September 2017

1 reference

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Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

29 September 2017

1 reference

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DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.

2 June 2018

1 reference

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A novel B-cell lineage-specific transcription factor present at early but not late stages of differentiation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472301

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472301

Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.

27 November 2018

1 reference

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Lymphoid-restricted development from multipotent candidate murine stem cells: distinct and complimentary functions of the c-kit and flt3-ligands.

27 November 2018

1 reference

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Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472301

Flt3 ligand supports the differentiation of early B cell progenitors in the presence of interleukin-11 and interleukin-7

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472301

Combined signaling through interleukin-7 receptors and flt3 but not c-kit potently and selectively promotes B-cell commitment and differentiation from uncommitted murine bone marrow progenitor cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472301

Flt3-ligand production by human bone marrow stromal cells

27 November 2018

1 reference

12 December 2020

Identification of CD19(-)B220(+)c-Kit(+)Flt3/Flk-2(+)cells as early B lymphoid precursors before pre-B-I cells in juvenile mouse bone marrow

1 reference

12 December 2020

Upregulation of Flt3 expression within the bone marrow Lin(-)Sca1(+)c-kit(+) stem cell compartment is accompanied by loss of self-renewal capacity

1 reference

12 December 2020

Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow

1 reference

12 December 2020

A B220+ CD117+ CD19- hematopoietic progenitor with potent lymphoid and myeloid developmental potential

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12 December 2020

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

1 reference

12 December 2020

Identifiers

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