IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation (Q28507103)

Impact, RWD domain protein

1 reference

Eukaryotic translation initiation factor 2, subunit 1 alpha

1 reference

Eukaryotic translation initiation factor 2 alpha kinase 4

1 reference

2

Evelyn Sattlegger

1 reference

24 January 2017

Cátia M. Pereira

1

1 reference

24 January 2017

Hao-Yuan Jiang

3

1 reference

24 January 2017

Beatriz M. Longo

4

1 reference

24 January 2017

Carolina B. Jaqueta

5

1 reference

24 January 2017

Alan G. Hinnebusch

6

1 reference

24 January 2017

Ronald C. Wek

7

1 reference

24 January 2017

Luiz E. A. M. Mello

8

1 reference

24 January 2017

Beatriz A. Castilho

Journal of Biological Chemistry

9

1 reference

24 January 2017

language of work or name

English

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publication date

5 August 2005

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24 January 2017

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24 January 2017

280

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24 January 2017

31

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24 January 2017

28316–28323

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24 January 2017

The unfolded protein response in nutrient sensing and differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

A neuronal isoform of CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Phosphorylation of translation initiation factor eIF2alpha in the brain during pilocarpine-induced status epilepticus in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Translation factors: in sickness and in health

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Biochemical mechanisms for translational regulation in synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Gene-specific regulation by general translation factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

The tRNA-binding moiety in GCN2 contains a dimerization domain that interacts with the kinase domain and is required for tRNA binding and kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Screening for imprinted genes by allelic message display: identification of a paternally expressed gene impact on mouse chromosome 18

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

GCD2, a translational repressor of the GCN4 gene, has a general function in the initiation of protein synthesis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Large-scale analysis of the human and mouse transcriptomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

Inducible enhancement of memory storage and synaptic plasticity in transgenic mice expressing an inhibitor of ATF4 (CREB-2) and C/EBP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200

GI Domain-mediated Association of the Eukaryotic Initiation Factor 2α Kinase GCN2 with Its Activator GCN1 Is Required for General Amino Acid Control in Budding Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M408571200