Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene (Q28507278)

24 January 2017

title

Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene (English)

1 reference

Polycystin 1, transient receptor potential channel interacting

24 January 2017

main subject

1 reference

GOA release 2020-03-11

1 reference

C. Boulter

1

1 reference

24 January 2017

S. Mulroy

2

1 reference

24 January 2017

S. Webb

3

1 reference

24 January 2017

S. Fleming

4

1 reference

24 January 2017

K. Brindle

5

1 reference

24 January 2017

R. Sandford

6

1 reference

24 January 2017

language of work or name

English

0 references

publication date

9 October 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

24 January 2017

published in

1 reference

24 January 2017

volume

98

1 reference

24 January 2017

issue

21

1 reference

24 January 2017

page(s)

12174–12179

1 reference

Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene

24 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Polycystin 1 is required for the structural integrity of blood vessels

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

19 March 2017

https://api.crossref.org/works/10.1073/PNAS.211191098

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Vascular expression of polycystin-2.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Mutation analysis of the entire PKD1 gene: genetic and diagnostic implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Polycystin-1, the gene product of PKD1, induces resistance to apoptosis and spontaneous tubulogenesis in MDCK cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Genomic circuits and the integrative biology of cardiac diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

New insights into the molecular pathophysiology of polycystic kidney disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

The polycystic kidney disease 1 gene product modulates Wnt signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Polycystin: in vitro synthesis, in vivo tissue expression, and subcellular localization identifies a large membrane-associated protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Identification and localization of polycystin, the PKD1 gene product

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Characterization and cell distribution of polycystin, the product of autosomal dominant polycystic kidney disease gene 1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

The etiology, pathogenesis, and treatment of autosomal dominant polycystic kidney disease: recent advances

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Polycystin, the polycystic kidney disease 1 protein, is expressed by epithelial cells in fetal, adult, and polycystic kidney

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Polycystic kidney disease: primary extracellular matrix abnormality or defective cellular differentiation?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Polycystin-2 expression is developmentally regulated.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Peptides from the PKD repeats of polycystin, the PKD1 gene product, modulate pattern formation in the developing kidney.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Somatic mutation in individual liver cysts supports a two-hit model of cystogenesis in autosomal dominant polycystic kidney disease.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

A human PKD1 transgene generates functional polycystin-1 in mice and is associated with a cystic phenotype

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Mutations of PKD1 in ADPKD2 cysts suggest a pathogenic effect of trans-heterozygous mutations.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Distinct and common developmental expression patterns of the murine Pkd2 and Pkd1 genes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Vascular expression of polycystin.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Murine Pkd1 is a developmentally regulated gene from morula to adulthood: role in tissue condensation and patterning

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Polycystin expression is temporally and spatially regulated during renal development.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=59787

Extrarenal manifestations of autosomal dominant polycystic kidney disease

27 November 2018

1 reference

12 December 2020

Immunological detection of polycystin-1 in human kidney

1 reference

12 December 2020

A kindred exhibiting cosegregation of an overlap connective tissue disorder and the chromosome 16 linked form of autosomal dominant polycystic kidney disease

1 reference

12 December 2020

Tubular basement membrane changes during induction and regression of drug-induced polycystic kidney disease

1 reference

12 December 2020

Adult, fetal, and polycystic kidney expression of polycystin, the polycystic kidney disease-1 gene product

1 reference

12 December 2020

Autosomal dominant polycystic kidney disease with anticipation and Caroli's disease associated with a PKD1 mutation Rapid Communication

1 reference

12 December 2020

The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1

1 reference

12 December 2020

Somatic inactivation of Pkd2 results in polycystic kidney disease

1 reference

12 December 2020

Cellular localization and tissue distribution of polycystin-1

1 reference

12 December 2020

Polycystin-1 expression in PKD1, early-onset PKD1, and TSC2/PKD1 cystic tissue

1 reference

12 December 2020

Expression of polycystin in mouse metanephros and extra-metanephric tissues

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.211191098

1 reference

ADS bibcode

2001PNAS...9812174B

0 references

1 reference

1 reference

1 reference