Bax and Bak independently promote cytochrome C release from mitochondria (Q28507634)

GOA release 2020-03-11

BCL2-antagonist/killer 1

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

1 reference

Eileen White

5

0 references

Craig B. Thompson

series ordinal

4

object named as

Craig Thompson

1 reference

24 January 2017

Kurt Degenhardt

1

1 reference

24 January 2017

Ramya Sundararajan

series ordinal

2

1 reference

24 January 2017

Tullia Lindsten

series ordinal

3

1 reference

24 January 2017

language of work or name

English

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publication date

19 April 2002

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24 January 2017

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24 January 2017

277

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24 January 2017

14127–14134

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24 January 2017

16

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24 January 2017

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Regulation of the cell cycle and apoptosis by the oncogenes of adenovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Identification and classification of p53-regulated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Bax directly induces release of cytochrome c from isolated mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

E1B 19K blocks Bax oligomerization and tumor necrosis factor alpha-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Regulation of the mitochondrial checkpoint in p53-mediated apoptosis confers resistance to cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

The polyproline region of p53 is required to activate apoptosis but not growth arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Cell death inhibition: keeping caspases in check

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

An induced proximity model for caspase-8 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Essential role for p53-mediated transcription in E1A-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

E1B 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Bcl-2 blocks p53-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

The E1B 19K protein blocks apoptosis by interacting with and inhibiting the p53-inducible and death-promoting Bax protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

The 19-Kilodalton Adenovirus E1B Transforming Protein Inhibits Programmed Cell Death and Prevents Cytolysis by Tumor Necrosis Factor α

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Induction by E1A oncogene expression of cellular susceptibility to lysis by TNF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Bak and Bax function to limit adenovirus replication through apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Structure-function comparisons of the proapoptotic protein Bax in yeast and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Structure of Bax: coregulation of dimer formation and intracellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Solution structure of BID, an intracellular amplifier of apoptotic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Channel formation by antiapoptotic protein Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Bcl-x(L) forms an ion channel in synthetic lipid membranes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200

Conformation of the Bax C-terminus regulates subcellular location and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109939200