TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways (Q28510527)

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English	TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways	scientific journal article

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scholarly article

1 reference

PubMed publication ID

25 January 2017

TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways (English)

1 reference

PubMed publication ID

25 January 2017

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toll-like receptor

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Interferon (alpha and beta) receptor 1

1 reference

GOA release 2020-03-11

Signal transducer and activator of transcription 2

1 reference

GOA release 2020-03-11

Signal transducer and activator of transcription 1

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

author name string

Jun Xu

1

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PubMed publication ID

25 January 2017

Philip W. Zoltick

2

1 reference

PubMed publication ID

25 January 2017

Ana M. Gamero

3

1 reference

PubMed publication ID

25 January 2017

Stefania Gallucci

4

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PubMed publication ID

25 January 2017

publication date

1 July 2014

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PubMed publication ID

25 January 2017

Journal of Leukocyte Biology

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PubMed publication ID

25 January 2017

96

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PubMed publication ID

25 January 2017

1

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PubMed publication ID

25 January 2017

93–103

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PubMed publication ID

25 January 2017

The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity

1 reference

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A diverse range of gene products are effectors of the type I interferon antiviral response

1 reference

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Trex1 prevents cell-intrinsic initiation of autoimmunity

1 reference

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Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus

1 reference

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The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death

1 reference

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Mechanisms of type-I- and type-II-interferon-mediated signalling

1 reference

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Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

1 reference

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

1 reference

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Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases

1 reference

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The exonuclease Trex1 restrains macrophage proinflammatory activation.

1 reference

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Molecular basis of DNA recognition in the immune system

1 reference

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Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

1 reference

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Myeloid dendritic cells from B6.NZM Sle1/Sle2/Sle3 lupus-prone mice express an IFN signature that precedes disease onset

1 reference

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Interferon-stimulated genes and their antiviral effector functions

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29 September 2017

Type I interferon and systemic lupus erythematosus

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Characterization of Trex1 induction by IFN-γ in murine macrophages.

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1 reference

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Three prime exonuclease I (TREX1) is Fos/AP-1 regulated by genotoxic stress and protects against ultraviolet light and benzo(a)pyrene-induced DNA damage

1 reference

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Dendritic cells transduced with lentiviral vectors expressing VIP differentiate into VIP-secreting tolerogenic-like DCs.

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The SET complex acts as a barrier to autointegration of HIV-1

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Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease

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Type I interferon signaling is involved in the spontaneous development of lupus-like disease in B6.Nba2 and (B6.Nba2 x NZW)F(1) mice.

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IL-4 suppresses dendritic cell response to type I interferons.

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Toll-like receptors control activation of adaptive immune responses

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12 December 2020

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Type I interferons produced by dendritic cells promote their phenotypic and functional activation

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https://pubmed.ncbi.nlm.nih.gov/24598055

12 December 2020

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Differential involvement of IFN-beta in Toll-like receptor-stimulated dendritic cell activation

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12 December 2020

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Unresponsiveness of MyD88-deficient mice to endotoxin

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https://pubmed.ncbi.nlm.nih.gov/24598055

12 December 2020

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Serum interferon levels in patients with systemic lupus erythematosus

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https://pubmed.ncbi.nlm.nih.gov/24598055

12 December 2020

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Identifiers

10.1189/JLB.2A0713-393RR

0 references

PMC publication ID

0 references

PubMed publication ID

1 reference

PubMed publication ID

25 January 2017

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