B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K (Q28510899)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K (English)

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

Phosphoinositide-3-kinase adaptor protein 1

19 January 2020

main subject

toll-like receptor

0 references

1 reference

GOA release 2020-03-11

author

Alexander W MacFarlane

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

author name string

Minjian Ni

1

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Michelle Toft

3

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Clifford A Lowell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Kerry S Campbell

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Jessica A Hamerman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

20 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

19 January 2020

published in

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

109

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

267-272

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

issue

1

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

19 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

The phosphoinositide 3-kinase pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

The regulation of IL-10 production by immune cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

Mammalian target of rapamycin and glycogen synthase kinase 3 differentially regulate lipopolysaccharide-induced interleukin-12 production in dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

Enhanced NK-cell development and function in BCAP-deficient mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/toll-like receptor 5 engagement in colonic epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

Opposite effects of wortmannin and 2-(4-morpholinyl)-8-phenyl-1(4H)-benzopyran-4-one hydrochloride on toll-like receptor-mediated nitric oxide production: negative regulation of nuclear factor-{kappa}B by phosphoinositide 3-kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

PI3K and negative regulation of TLR signaling.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

Phosphatidylinositol 3-kinase activity negatively regulates stability of cyclooxygenase 2 mRNA.

29 September 2017

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111957108

Role of the phosphatidylinositol 3 kinase-Akt pathway in the regulation of IL-10 and IL-12 by Porphyromonas gingivalis lipopolysaccharide

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111957108

SHIP negatively regulates Flt3L-derived dendritic cell generation and positively regulates MyD88-independent TLR-induced maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111957108

Inhibition of phosphoinositide 3-kinase enhances TRIF-dependent NF-kappa B activation and IFN-beta synthesis downstream of Toll-like receptor 3 and 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111957108

Tyrosine phosphorylation of B-cell adaptor for phosphoinositide 3-kinase is required for Akt activation in response to CD19 engagement

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111957108

Regulation of B-cell development by BCAP and CD19 through their binding to phosphoinositide 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111957108

Essential immunoregulatory role for BCAP in B cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111957108

Effective clearance of intracellularLeishmania majorin vivo requires Pten in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111957108

Syk is required for integrin signaling in neutrophils

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252908

Toll-like receptor 2 (TLR2) and TLR4 differentially activate human dendritic cells

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22187458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

PI3K-mediated negative feedback regulation of IL-12 production in DCs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22187458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intracellular network of phosphatidylinositol 3-kinase, mammalian target of the rapamycin/70 kDa ribosomal S6 kinase 1, and mitogen-activated protein kinases pathways for regulating mycobacteria-induced IL-23 expression in human macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22187458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1111957108

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

ADS bibcode

2012PNAS..109..267N

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22187458%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

2 references