Synapse-associated protein-97 mediates alpha-secretase ADAM10 trafficking and promotes its activity (Q28511294)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673742&resulttype=core&format=json

A disintegrin and metallopeptidase domain 10

11 May 2020

main subject

1 reference

Discs large MAGUK scaffold protein 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Fabrizio Gardoni

2

1 reference

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11 May 2020

Daniela Mauceri

3

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11 May 2020

Carlo Sala

9

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11 May 2020

Monica Di Luca

11

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11 May 2020

author name string

Elena Marcello

1

2 references

25 January 2017

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11 May 2020

Stefano Romorini

4

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11 May 2020

Andreas Jeromin

5

2 references

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11 May 2020

Roberta Epis

6

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11 May 2020

Flaminio Cattabeni

8

2 references

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11 May 2020

Alessandro Padovani

10

2 references

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11 May 2020

Barbara Borroni

7

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11 May 2020

language of work or name

English

0 references

publication date

14 February 2007

1 reference

25 January 2017

Journal of Neuroscience

2 references

25 January 2017

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11 May 2020

volume

27

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issue

7

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page(s)

1682-1691

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Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models

11 May 2020

cites work

1 reference

12 December 2020

Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease

1 reference

12 December 2020

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

12 December 2020

Phenotypic down-regulation of glutamate receptor subunit GluR1 in Alzheimer's disease

1 reference

12 December 2020

Tissue inhibitors of metalloproteinases: evolution, structure and function

1 reference

12 December 2020

The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3

1 reference

12 December 2020

Molecular determinants of presynaptic active zones

1 reference

12 December 2020

Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein.

1 reference

12 December 2020

Hippocampal synaptic plasticity involves competition between Ca2+/calmodulin-dependent protein kinase II and postsynaptic density 95 for binding to the NR2A subunit of the NMDA receptor

1 reference

12 December 2020

BACE2 functions as an alternative alpha-secretase in cells

1 reference

12 December 2020

Regulation of dendritic spine morphology and synaptic function by Shank and Homer

1 reference

12 December 2020

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

12 December 2020

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

1 reference

12 December 2020

Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death

1 reference

12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

12 December 2020

Drebrin, a dendritic spine protein, is manifold decreased in brains of patients with Alzheimer's disease and Down syndrome

1 reference

12 December 2020

A non-amyloidogenic function of BACE-2 in the secretory pathway

1 reference

12 December 2020

Lack of PSD-95 drives hippocampal neuronal cell death through activation of an alpha CaMKII transduction pathway

1 reference

12 December 2020

Alzheimer's disease is a synaptic failure

1 reference

12 December 2020

Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions

1 reference

12 December 2020

ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles

1 reference

12 December 2020

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

1 reference

12 December 2020

APP processing and synaptic function

1 reference

12 December 2020

Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes

1 reference

12 December 2020

Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

1 reference

12 December 2020

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

12 December 2020

Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory

1 reference

12 December 2020

CaMKII-dependent phosphorylation regulates SAP97/NR2A interaction

1 reference

12 December 2020

Accumulation of amyloid precursor protein in neurons after intraventricular injection of colchicine

1 reference

12 December 2020

Calcium/calmodulin-dependent protein kinase II phosphorylation drives synapse-associated protein 97 into spines.

1 reference

12 December 2020

A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model

1 reference

12 December 2020

Molecular pathways to neurodegeneration

1 reference

12 December 2020

Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines.

1 reference

12 December 2020

PDZ domain proteins of synapses

1 reference

12 December 2020

Quaternary structure, protein dynamics, and synaptic function of SAP97 controlled by L27 domain interactions

1 reference

12 December 2020

Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence

1 reference

12 December 2020

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

1 reference

12 December 2020

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

1 reference

12 December 2020

ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling

1 reference

12 December 2020

Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited

1 reference

12 December 2020

Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease.

1 reference

12 December 2020

Regulation of NMDA receptor trafficking by amyloid-beta

1 reference

12 December 2020

Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans

1 reference

12 December 2020

A basolateral sorting signal directs ADAM10 to adherens junctions and is required for its function in cell migration

1 reference

12 December 2020

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

1 reference

12 December 2020

Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein

1 reference

12 December 2020

Deterioration threshold of synaptic morphology in aging and senile dementia of Alzheimer's type.

1 reference

12 December 2020

Disappearance of actin-binding protein, drebrin, from hippocampal synapses in Alzheimer's disease

1 reference

12 December 2020

Trafficking of cell-surface beta-amyloid precursor protein: evidence that a sorting intermediate participates in synaptic vesicle recycling

1 reference

12 December 2020

Quantitation of AMPA receptor surface expression in cultured hippocampal neurons.

1 reference

12 December 2020

Increased secretion of the amino-terminal fragment of amyloid precursor protein in brains of rats with a constitutive up-regulation of protein kinase C.

1 reference

12 December 2020

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

1 reference

12 December 2020

Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor

1 reference

12 December 2020

10.1523/JNEUROSCI.3439-06.2007

Identifiers

DOI

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673742&resulttype=core&format=json

11 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673742&resulttype=core&format=json

11 May 2020

2 references

25 January 2017