CDK6 kinase activity is required for thymocyte development (Q28512218)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

CDK6 kinase activity is required for thymocyte development (English)

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

hematopoietic stem cell homeostasis

29 January 2020

main subject

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0061484

Cyclin-dependent kinase 4

1 reference

Cyclin-dependent kinase 2

1 reference

Lymphocyte antigen 6 complex, locus A

1 reference

CD44 antigen

1 reference

Annexin A5

1 reference

CD8 antigen, alpha chain

1 reference

Cyclin-dependent kinase 6

1 reference

CD4 antigen

1 reference

Interleukin 2 receptor, alpha chain

1 reference

CD27 antigen

1 reference

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Amit Deshpande

2

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Nicolette Schlichting

3

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Changchuin Mao

5

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Guo-Fu Hu

7

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Fotini Gounari

9

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Miaofen G Hu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Elisabeth A Hinds

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Richard A Van Etten

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Philip W Hinds

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

20 April 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

number of pages

12

1 reference

based on heuristic

inferred from page(s)

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

117

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

23

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

6120-6131

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation

29 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Loss of adenomatous polyposis coli gene function disrupts thymic development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Structural basis for CDK6 activation by a virus-encoded cyclin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

cdk6 can shorten G(1) phase dependent upon the N-terminal INK4 interaction domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

CDK inhibitors: positive and negative regulators of G1-phase progression

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Inhibitors of mammalian G1 cyclin-dependent kinases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Notch signaling mediates G1/S cell-cycle progression in T cells via cyclin D3 and its dependent kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Molecular dissection of prethymic progenitor entry into the T lymphocyte developmental pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

From cell cycle to differentiation: an expanding role for cdk6.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Induction of T cell development from hematopoietic progenitor cells by delta-like-1 in vitro.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

The development of functionally responsive T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

A conserved IL-2 responsive enhancer in the IL-2R alpha gene

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

CD27 cooperates with the pre-T cell receptor in the regulation of murine T cell development

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Notch signaling augments T cell responsiveness by enhancing CD25 expression

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Stem cell repopulation efficiency but not pool size is governed by p27(kip1).

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Differential expression of cyclin-dependent kinase 6 in cortical thymocytes and T-cell lymphoblastic lymphoma/leukemia.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3122937

Tracing lymphopoiesis with the aid of a pTα-controlled reporter gene

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21508411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of G1-phase cell cycle genes during hematopoietic lineage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21508411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2010-08-300517

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21508411%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

2 references

25 January 2017