A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death (Q28513626)

Rous sarcoma oncogene

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Mitogen-activated protein kinase 14

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Thymoma viral proto-oncogene 1

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Journal of Biological Chemistry

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3

Karim Benihoud

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25 January 2017

Rodolphe Auger

1

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25 January 2017

Iris Motta

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2

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25 January 2017

David M. Ojcius

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4

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25 January 2017

Jean M. Kanellopoulos

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5

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25 January 2017

language of work or name

English

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publication date

29 July 2005

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25 January 2017

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25 January 2017

280

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25 January 2017

30

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28142–28151

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25 January 2017

Hetero-oligomeric assembly of P2X receptor subunits. Specificities exist with regard to possible partners

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Molecular physiology of P2X receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Spontaneous cell fusion in macrophage cultures expressing high levels of the P2Z/P2X7 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

P2X(7) receptor and polykarion formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Maturation and release of interleukin-1beta by lipopolysaccharide-primed mouse Schwann cells require the stimulation of P2X7 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Altered cytokine production in mice lacking P2X(7) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Rapid secretion of interleukin-1beta by microvesicle shedding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Inhibition of chlamydial infectious activity due to P2X7R-dependent phospholipase D activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Kinetics of cell lysis, dye uptake and permeability changes in cells expressing the rat P2X7 receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Extracellular ATP as a trigger for apoptosis or programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Role of the purinergic P2Z receptor in spontaneous cell death in J774 macrophage cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Priming of macrophages with lipopolysaccharide potentiates P2X7-mediated cell death via a caspase-1-dependent mechanism, independently of cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Transient up-regulation of P2Y2 nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

The Pro-451 to Leu polymorphism within the C-terminal tail of P2X7 receptor impairs cell death but not phospholipase D activation in murine thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Mechanisms of P2X7 receptor-mediated ERK1/2 phosphorylation in human astrocytoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1 beta release

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

The nucleotide receptor P2X7 mediates actin reorganization and membrane blebbing in RAW 264.7 macrophages via p38 MAP kinase and Rho.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Extracellular ATP activates transcription factor NF-kappaB through the P2Z purinoreceptor by selectively targeting NF-kappaB p65

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

P2X7/P2Z purinoreceptor-mediated activation of transcription factor NFAT in microglial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Sequence dependency of the internalization and distribution of phosphorothioate oligonucleotides in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Ionic effects on human recombinant P2X7 receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Pharmacological characterization of recombinant human and rat P2X receptor subtypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Proteomic and functional evidence for a P2X7 receptor signalling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Proteasome regulation of activation-induced T cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Mammalian MAP kinase signalling cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Complement anaphylatoxin C5a neuroprotects through mitogen-activated protein kinase-dependent inhibition of caspase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Signaling through P2X7 receptor in human T cells involves p56lck, MAP kinases, and transcription factors AP-1 and NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

P2X7 receptor activates extracellular signal-regulated kinases ERK1 and ERK2 independently of Ca2+ influx

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Mitogen-activated protein kinase and caspase signaling pathways are required for P2X7 receptor (P2X7R)-induced pore formation in human THP-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Are second messengers crucial for opening the pore associated with P2X7 receptor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Threonine-124 and phenylalanine-448 in Citrobacter freundii tyrosine phenol-lyase are necessary for activity with L-tyrosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Production and release of neuroprotective tumor necrosis factor by P2X7 receptor-activated microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

P2X7 receptors stimulate AKT phosphorylation in astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200

Duration and Strength of Extracellular Signal-Regulated Kinase Signals Are Altered During Positive Versus Negative Thymocyte Selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501290200