The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice (Q28513847)

1

1 reference

25 January 2017

Junwang Xu

2

1 reference

25 January 2017

Min Min Lu

3

1 reference

25 January 2017

Jonathan A. Epstein

Journal of Clinical Investigation

4

1 reference

25 January 2017

language of work or name

English

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publication date

1 September 2006

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25 January 2017

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25 January 2017

116

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25 January 2017

9

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25 January 2017

2378–2384

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25 January 2017

describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1533876/fullTextXML

inferred from PubMed Central ID database lookup

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Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain

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NF1 tumor suppressor gene function: narrowing the GAP

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Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

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Recent advances in understanding the antineoplastic mechanisms of farnesyltransferase inhibitors

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The NF1 tumor suppressor critically regulates TSC2 and mTOR.

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Neurofibromin GTPase-activating protein-related domains restore normal growth in Nf1-/- cells

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Minor lesion mutational spectrum of the entire NF1 gene does not explain its high mutability but points to a functional domain upstream of the GAP-related domain

29 September 2017

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Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1.

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NF1 modulates the effects of Ras oncogenes: evidence of other NF1 function besides its GAP activity

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Mutations in the GAP-related domain impair the ability of neurofibromin to associate with microtubules.

2 June 2018

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Mutational and functional analysis of the neurofibromatosis type 1 (NF1) gene.

2 June 2018

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Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis

2 June 2018

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Farnesyl and geranylgeranyl transferase inhibitors induce G1 arrest by targeting the proteasome.

2 June 2018

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Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexiform neurofibromas

27 November 2018

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Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors

27 November 2018

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27 November 2018

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Different mutations in the NF1 gene are associated with Neurofibromatosis–Noonan syndrome (NFNS)

27 November 2018

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A neurofibromatosis-1-regulated pathway is required for learning in Drosophila

27 November 2018

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NF1 mutation analysis using a combined heteroduplex/SSCP approach.

27 November 2018

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Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders

27 November 2018

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Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides

27 November 2018

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Renovascular disease and hypertension in children with neurofibromatosis

27 November 2018

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12 December 2020

Cardiovascular malformations and other cardiovascular abnormalities in neurofibromatosis 1

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12 December 2020

Neurofibromatosis type 1

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12 December 2020

A targeted X-linked CMV-Cre line

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12 December 2020

Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia

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12 December 2020

Genetic and phenotypic characterization of tumor cells derived from malignant peripheral nerve sheath tumors of neurofibromatosis type 1 patients

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12 December 2020

Noonan phenotype associated with neurofibromatosis

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12 December 2020

Neurofibromatosis update

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12 December 2020

Neurofibromin modulation of ras activity is required for normal endocardial-mesenchymal transformation in the developing heart

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12 December 2020

Mutational analysis of N-RAS and GAP-related domain of the neurofibromatosis type 1 gene in chronic myelogenous leukemia

1 reference

12 December 2020