A cationic-independent mannose 6-phosphate receptor inhibitor (PXS64) ameliorates kidney fibrosis by inhibiting activation of transforming growth factor-β1 (Q28543256)

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English	A cationic-independent mannose 6-phosphate receptor inhibitor (PXS64) ameliorates kidney fibrosis by inhibiting activation of transforming growth factor-β1	scientific article

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scholarly article

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A cationic-independent mannose 6-phosphate receptor inhibitor (PXS64) ameliorates kidney fibrosis by inhibiting activation of transforming growth factor-β1 (English)

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author name string

Jie Zhang

1

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Muh Geot Wong

2

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May Wong

3

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Simon Gross

4

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Jason Chen

5

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Carol Pollock

6

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Sonia Saad

7

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language of work or name

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publication date

2015

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10

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2

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e0116888

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copyright license

Creative Commons Attribution 4.0 International

6 February 2015

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April 2022 Public Data File from Crossref

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Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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19 March 2017

Redox-mediated activation of latent transforming growth factor-beta 1

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19 March 2017

Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium

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Myofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease

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29 September 2017

Norcantharidin inhibits renal interstitial fibrosis by blocking the tubular epithelial-mesenchymal transition

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29 September 2017

How does TGF-β mediate tubulointerstitial fibrosis?

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29 September 2017

The role of IL-7 in renal proximal tubule epithelial cells fibrosis

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29 September 2017

Cation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-beta1.

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29 September 2017

The suffocating kidney: tubulointerstitial hypoxia in end-stage renal disease

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29 September 2017

Mycophenolic acid may delay allograft fibrosis by inhibiting transforming growth factor-beta1-induced activation of Nox-2 through the nuclear factor-kappaB pathway

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29 September 2017

Review: renal protection by inhibition of the renin-angiotensin-aldosterone system

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29 September 2017

TGF-beta signal transduction in chronic kidney disease

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29 September 2017

Proteomic analysis of lysosomal acid hydrolases secreted by osteoclasts: implications for lytic enzyme transport and bone metabolism

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29 September 2017

The accumulation of extracellular matrix in the kidney: consequences on cellular function.

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29 September 2017

Obstructive nephropathy and renal fibrosis

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29 September 2017

TGF-beta signaling in renal disease

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29 September 2017

Transforming growth factor beta signal transduction.

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29 September 2017

Molecular basis of renal fibrosis

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29 September 2017

Interstitial pathomechanisms underlying progressive tubulointerstitial damage

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29 September 2017

Transforming growth factor beta in bovine milk: concentration, stability and molecular mass forms

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29 September 2017

Determination of hydroxyproline

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29 September 2017

The Role of the Interstitium of the Renal Cortex in Renal Disease

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29 September 2017

Disruption of Smad4 impairs TGF-β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro.

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21 January 2018

Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock.

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21 January 2018

The effect of Mannose-6-Phosphate on recovery after sciatic nerve repair.

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21 January 2018

Pathophysiology of unilateral ureteral obstruction: studies from Charlottesville to New York

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21 January 2018

Inhibition of TGF-β1/Smad signal pathway is involved in the effect of Cordyceps sinensis against renal fibrosis in 5/6 nephrectomy rats

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21 January 2018

Chronic kidney disease progression.

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21 January 2018

Histopathological and biomechanical parameters of repaired rat achilles tendons treated with and without mannose-6-phosphate.

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27 November 2018

Cross-talk between ERK MAP kinase and Smad signaling pathways enhances TGF-beta-dependent responses in human mesangial cells

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27 November 2018

Mannose-6-phosphate, an inhibitor of transforming growth factor-beta, improves range of motion after flexor tendon repair

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12 December 2020

based on heuristic

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Effects of proteasome inhibitors on rat renal fibrosis in vitro and in vivo

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https://pubmed.ncbi.nlm.nih.gov/25658916

12 December 2020

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M6P/IGFII-receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor-beta1

1 reference

https://pubmed.ncbi.nlm.nih.gov/25658916

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type 2 diabetic patients with nephropathy show structural-functional relationships that are similar to type 1 disease

1 reference

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12 December 2020

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Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease

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https://pubmed.ncbi.nlm.nih.gov/25658916

12 December 2020

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Phosphosugars are potent inhibitors of central nervous system inflammation

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https://pubmed.ncbi.nlm.nih.gov/25658916

12 December 2020

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Identifiers

10.1371/JOURNAL.PONE.0116888

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2015PLoSO..1016888Z

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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