Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling (Q28564173)

31 January 2017

title

Tyrosine phosphorylation of phosphoinositide-dependent kinase 1 by the insulin receptor is necessary for insulin metabolic signaling (English)

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31 January 2017

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Vincenzo Corbo

6

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Pietro Formisano

object named as

Pietro Formisano

11

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author name string

Francesca Fiory

1

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31 January 2017

Anna Teresa Alberobello

2

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31 January 2017

Claudia Miele

3

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31 January 2017

Francesco Oriente

4

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31 January 2017

Iolanda Esposito

5

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31 January 2017

Menotti Ruvo

7

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31 January 2017

Barbara Tizzano

8

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31 January 2017

Thomas E. Rasmussen

9

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31 January 2017

Steen Gammeltoft

10

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31 January 2017

Francesco Beguinot

12

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31 January 2017

language of work or name

English

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publication date

1 December 2005

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Molecular and Cellular Biology

31 January 2017

published in

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31 January 2017

volume

25

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31 January 2017

issue

24

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31 January 2017

page(s)

10803–10814

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

31 January 2017

cites work

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Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells

19 March 2017

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19 March 2017

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Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

19 March 2017

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Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

19 March 2017

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Primary structure, tissue distribution, and expression of mouse phosphoinositide-dependent protein kinase-1, a protein kinase that phosphorylates and activates protein kinase Czeta

19 March 2017

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Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)

19 March 2017

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19 March 2017

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Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B

19 March 2017

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Direct activation of the phosphatidylinositol 3'-kinase by the insulin receptor

19 March 2017

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PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle

19 March 2017

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Roles of 3-phosphoinositide-dependent kinase 1 in the regulation of endothelial nitric-oxide synthase phosphorylation and function by heat shock protein 90.

29 September 2017

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Overexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action

29 September 2017

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The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation

29 September 2017

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Phosphoinositide 3-kinase: the protein kinase that time forgot

29 September 2017

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Phosphoinositide-dependent kinase-2 is a distinct protein kinase enriched in a novel cytoskeletal fraction associated with adipocyte plasma membranes

29 September 2017

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A new molecular target of insulin action: regulating the pivotal PDK1.

29 September 2017

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Characterization of phosphatidylinositol 3-kinase-dependent phosphorylation of the hydrophobic motif site Thr(389) in p70 S6 kinase 1.

29 September 2017

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3'-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling

29 September 2017

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29 September 2017

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Cellular signaling: pivoting around PDK-1.

29 September 2017

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Effect of phosphoinositide-dependent kinase 1 on protein kinase B translocation and its subsequent activation

29 September 2017

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Oxidative stress and vanadate induce tyrosine phosphorylation of phosphoinositide-dependent kinase 1 (PDK1).

29 September 2017

1 reference

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The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

29 September 2017

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In L6 skeletal muscle cells, glucose induces cytosolic translocation of protein kinase C-alpha and trans-activates the insulin receptor kinase

29 September 2017

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Mechanism of protein kinase B activation by cyclic AMP-dependent protein kinase

29 September 2017

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Intracellular signalling: PDK1--a kinase at the hub of things

29 September 2017

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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro

29 September 2017

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In skeletal muscle, glucose storage and oxidation are differentially impaired by the IR1152 mutant receptor.

29 September 2017

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Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

29 September 2017

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Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids

29 September 2017

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Activation of phosphatidylinositol 3-kinase by insulin

29 September 2017

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Protein kinase C-zeta and protein kinase B regulate distinct steps of insulin endocytosis and intracellular sorting

29 September 2017

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Requirement for 3-phosphoinositide-kependent dinase-1 (PDK-1) in insulin-induced glucose uptake in immortalized brown adipocytes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316974

In NIH-3T3 fibroblasts, insulin receptor interaction with specific protein kinase C isoforms controls receptor intracellular routing

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316974

Mutation in a conserved motif next to the insulin receptor key autophosphorylation sites de-regulates kinase activity and impairs insulin action

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316974

Insulin-induced activation of phosphatidyl inositol 3-kinase. Demonstration that the p85 subunit binds directly to the COOH terminus of the insulin receptor in intact cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316974

Insulin-stimulated translocation of glucose transporters in the isolated rat adipose cells: Characterization of subcellular fractions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316974

Properties of a human insulin receptor with a COOH-terminal truncation. II. Truncated receptors have normal kinase activity but are defective in signaling metabolic effects

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316974

Differential sorting of two glucose transporters expressed in insulin-sensitive cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316974

Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1316974

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/16314505

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Peroxovanadate induces tyrosine phosphorylation of phosphoinositide-dependent protein kinase-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16314505

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The insulin receptor functions normally in Chinese hamster ovary cells after truncation of the C terminus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16314505

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.25.24.10803-10814.2005

1 reference

31 January 2017

0 references

1 reference