STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation (Q28575333)

9

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Chantal Mathieu

8

object named as

Chantal Mathieu

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31 January 2017

Fabrice Moore

1

1 reference

31 January 2017

Najib Naamane

2

1 reference

31 January 2017

Maikel L. Colli

3

1 reference

31 January 2017

Thomas Bouckenooghe

4

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31 January 2017

Esteban N. Gurzov

6

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31 January 2017

Mariana Igoillo-Esteve

7

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31 January 2017

Thomas Thykjaer

10

1 reference

31 January 2017

Torben F. Ørntoft

11

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31 January 2017

Decio L. Eizirik

Journal of Biological Chemistry

12

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31 January 2017

language of work or name

English

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publication date

14 January 2011

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31 January 2017

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31 January 2017

286

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31 January 2017

929–941

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31 January 2017

2

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31 January 2017

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Summaries of Affymetrix GeneChip probe level data

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Nuclear factor kappa B is involved in lipopolysaccharide-stimulated induction of interferon regulatory factor-1 and GAS/GAF DNA-binding in human umbilical vein endothelial cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

A comprehensive analysis of cytokine-induced and nuclear factor-kappa B-dependent genes in primary rat pancreatic beta-cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

The BCL-2 protein family: opposing activities that mediate cell death

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Beta cell apoptosis in diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Frequency-modulated nuclear localization bursts coordinate gene regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Increased expression of CCL2 in insulin-producing cells of transgenic mice promotes mobilization of myeloid cells from the bone marrow, marked insulitis, and diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Cytokine signalling in the beta-cell: a dual role for IFNgamma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

JAK1-STAT1-STAT3, a key pathway promoting proliferation and preventing premature differentiation of myoblasts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Role of STAT3 in type I interferon responses. Negative regulation of STAT1-dependent inflammatory gene activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Stress-controlled transcription factors, stress-induced genes and stress tolerance in budding yeast

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-gamma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Notch signaling: a mediator of beta-cell de-differentiation in diabetes?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Disruption of the gamma-interferon signaling pathway at the level of signal transducer and activator of transcription-1 prevents immune destruction of beta-cells

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

Interferon regulatory factor-1 is a key transcription factor in murine beta cells under immune attack

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

Decrease in {beta}-cell proliferation precedes apoptosis during diabetes development in bio-breeding/worcester rat: beneficial role of Exendin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

Critical role for DP5/Harakiri, a Bcl-2 homology domain 3-only Bcl-2 family member, in axotomy-induced neuronal cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

Expression pattern of a novel death-promoting gene, DP5, in the developing murine nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

Suppressor of cytokine signaling-1 overexpression protects pancreatic beta cells from CD8+ T cell-mediated autoimmune destruction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

Islet inflammation and CXCL10 in recent-onset type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

Inhibition of STAT1 accelerates bone fracture healing

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020778

Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitope

27 November 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.162131

Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis

21 January 2018

1 reference

12 December 2020

Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays

1 reference

12 December 2020

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

1 reference

12 December 2020

Pathologic anatomy of the pancreas in juvenile diabetes mellitus

1 reference

12 December 2020

Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases

1 reference

12 December 2020

Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation

1 reference

12 December 2020

Deletion of STAT-1 pancreatic islets protects against streptozotocin-induced diabetes and early graft failure but not against late rejection

1 reference

12 December 2020

Essential Role for Signal Transducer and Activator of Transcription-1 in Pancreatic -Cell Death and Autoimmune Type 1 Diabetes of Nonobese Diabetic Mice

1 reference

12 December 2020

Induction of nuclear factor-kappaB and its downstream genes by TNF-alpha and IL-1beta has a pro-apoptotic role in pancreatic beta cells

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.162131

1 reference

release_slvavudd3rcrzahadqyhm66woi

4006101

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/slvavudd3rcrzahadqyhm66woi

24 November 2022

mapped directly with Wikidata item

4006101

1 reference

1 reference

1 reference