The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells (Q28575562)

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English	The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

21 June 2017

The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells (English)

1 reference

Europe PubMed Central

21 June 2017

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1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Jonathan Schisler

1

object named as

Jonathan C Schisler

1 reference

Europe PubMed Central

21 June 2017

Christopher B Newgard

11

object named as

Christopher B Newgard

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Europe PubMed Central

21 June 2017

author name string

Per Bo Jensen

2

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Europe PubMed Central

21 June 2017

Filip Krag Knop

5

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Europe PubMed Central

21 June 2017

Shiro Takekawa

6

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Europe PubMed Central

21 June 2017

Michael German

7

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Europe PubMed Central

21 June 2017

Danhong Lu

9

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Europe PubMed Central

21 June 2017

David G Taylor

3

1 reference

Europe PubMed Central

21 June 2017

Thomas C Becker

4

1 reference

Europe PubMed Central

21 June 2017

Gordon C Weir

8

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Europe PubMed Central

21 June 2017

Raghavendra G Mirmira

10

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Europe PubMed Central

21 June 2017

language of work or name

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publication date

9 May 2005

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Europe PubMed Central

21 June 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

21 June 2017

102

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Europe PubMed Central

21 June 2017

20

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Europe PubMed Central

21 June 2017

7297-7302

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Europe PubMed Central

21 June 2017

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

17 March 2017

Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

17 March 2017

Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

17 March 2017

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

17 March 2017

Cloning and DNA-binding properties of the rat pancreatic beta-cell-specific factor Nkx6.1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

17 March 2017

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

17 March 2017

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

7 April 2017

An adenovirus vector for efficient RNA interference-mediated suppression of target genes in insulinoma cells and pancreatic islets of langerhans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Covalent Histone Modifications Underlie the Developmental Regulation of Insulin Gene Transcription in Pancreatic β Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Gene expression cascades in pancreatic development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Exogenous nitric oxide and endogenous glucose-stimulated beta-cell nitric oxide augment insulin release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Quantitative assessment of gene targeting in vitro and in vivo by the pancreatic transcription factor, Pdx1. Importance of chromatin structure in directing promoter binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Expression of neurogenin3 reveals an islet cell precursor population in the pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Leptin inhibits insulin secretion induced by cellular cAMP in a pancreatic B cell line (INS-1 cells).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Genes induced by growth arrest in a pancreatic beta cell line: identification by analysis of cDNA arrays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Lipid rather than glucose metabolism is implicated in altered insulin secretion caused by oleate in INS-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Engineering of glycerol-stimulated insulin secretion in islet beta cells. Differential metabolic fates of glucose and glycerol provide insight into mechanisms of stimulus-secretion coupling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Regulation of insulin secretion from novel engineered insulinoma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Insulin-secreting cell lines: classification, characteristics and potential applications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

TNF-alpha inhibits glucose-induced insulin secretion in a pancreatic beta-cell line (INS-1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Adenovirus-mediated transfer of low density lipoprotein receptor gene acutely accelerates cholesterol clearance in normal mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Use of recombinant adenovirus for metabolic engineering of mammalian cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

29 September 2017

Glucose Sensitivity and Metabolism-Secretion Coupling Studied during Two-Year Continuous Culture in INS-1E Insulinoma Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

3 June 2018

Beta-cell differentiation factor Nkx6.1 contains distinct DNA binding interference and transcriptional repression domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

3 June 2018

Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

3 June 2018

Selection of insulinoma cell lines with resistance to interleukin-1beta- and gamma-interferon-induced cytotoxicity.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502168102

21 January 2018

mRNA Profiling of Rat Islet Tumors Reveals Nkx 6.1 as a β-Cell-specific Homeodomain Transcription Factor

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502168102

21 January 2018

Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502168102

21 January 2018

Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502168102

21 January 2018

The transcription factor SREBP-1c is instrumental in the development of beta-cell dysfunction

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502168102

21 January 2018

Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0502168102

21 January 2018

Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

27 November 2018

Accelerated titering of adenoviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1091752

27 November 2018

Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15883383

12 December 2020

based on heuristic

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Global profiling of double stranded RNA- and IFN-?-induced genes in rat pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15883383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of microarray analysis to unveil transcription factor and gene networks contributing to Beta cell dysfunction and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15883383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of glucose transport into rat islet cells by immunoglobulins from patients with new-onset insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15883383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.0502168102

1 reference

Europe PubMed Central

21 June 2017

2005PNAS..102.7297S

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1 reference

Europe PubMed Central

21 June 2017

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