PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity (Q28582308)

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8 November 2019

title

PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity (English)

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31 January 2017

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8 November 2019

1 reference

4

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8 November 2019

Shigeo Ohno

13

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8 November 2019

author name string

Michihiro Matsumoto

1

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8 November 2019

Wataru Ogawa

2

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8 November 2019

Kazunori Akimoto

3

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8 November 2019

Kazuaki Miyake

5

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8 November 2019

Kensuke Furukawa

6

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8 November 2019

Yoshitake Hayashi

7

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8 November 2019

Haruhisa Iguchi

8

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8 November 2019

Yasushi Matsuki

9

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8 November 2019

Ryuji Hiramatsu

10

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8 November 2019

Hitoshi Shimano

11

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8 November 2019

Nobuhiro Yamada

12

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8 November 2019

Masato Kasuga

14

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8 November 2019

Tetsuo Noda

15

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8 November 2019

language of work or name

English

0 references

publication date

1 September 2003

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Journal of Clinical Investigation

8 November 2019

published in

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8 November 2019

volume

112

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8 November 2019

page(s)

935-944

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8 November 2019

issue

6

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Protein kinase C lambda/iota (PKClambda/iota): a PKC isotype essential for the development of multicellular organisms

8 November 2019

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Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

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ADD1/SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose

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Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

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PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

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Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

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27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

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A Crucial Role of Sterol Regulatory Element-binding Protein-1 in the Regulation of Lipogenic Gene Expression by Polyunsaturated Fatty Acids

27 November 2018

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12 December 2020

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

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12 December 2020

Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients

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12 December 2020

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction

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12 December 2020

Effects of nutrients and hormones on transcriptional and post-transcriptional regulation of fatty acid synthase in rat liver

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12 December 2020

Identifiers

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31 January 2017

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8 November 2019

1 reference

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8 November 2019

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