Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization (Q28585571)

24 June 2017

Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization (English)

1 reference

T-lymphoma invasion and metastasis-inducing protein 1

24 June 2017

0 references

1 reference

Nectin cell adhesion molecule 1

1 reference

Rac family small GTPase 1

1 reference

Nectin cell adhesion molecule 2

1 reference

Platelet-activating factor acetylhydrolase, isoform 1b, subunit 1

1 reference

Dishevelled segment polarity protein 2

1 reference

Pericentriolar material 1

1 reference

Nectin cell adhesion molecule 3

1 reference

author name string

Lixia Liu

2

1 reference

24 June 2017

Jianyi Lee

3

1 reference

24 June 2017

Cynthia Grimsley-Myers

4

1 reference

24 June 2017

Xiaowei Lu

5

1 reference

24 June 2017

Conor W Sipe

1

1 reference

24 June 2017

language of work or name

English

0 references

publication date

1 April 2013

1 reference

24 June 2017

11

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inferred from page(s)

published in

Development

1 reference

24 June 2017

140

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24 June 2017

8

1 reference

24 June 2017

1785-1795

1 reference

describes a project that uses

24 June 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3621493/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Lis1 acts as a "clutch" between the ATPase and microtubule-binding domains of the dynein motor.

1 reference

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Sensing sound: molecules that orchestrate mechanotransduction by hair cells

17 March 2017

1 reference

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Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain

17 March 2017

1 reference

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The small GTPase Rac1 regulates auditory hair cell morphogenesis

17 March 2017

1 reference

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Ciliary proteins link basal body polarization to planar cell polarity regulation

17 March 2017

1 reference

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Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Nudel contributes to microtubule anchoring at the mother centriole and is involved in both dynein-dependent and -independent centrosomal protein assembly

17 March 2017

1 reference

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LIS1 RNA interference blocks neural stem cell division, morphogenesis, and motility at multiple stages

17 March 2017

1 reference

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PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates

17 March 2017

1 reference

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Disregulated RhoGTPases and Actin Cytoskeleton Contribute to the Migration Defect in Lis1-Deficient Neurons

17 March 2017

1 reference

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Multiple dose-dependent effects of Lis1 on cerebral cortical development

17 March 2017

1 reference

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Assembly of centrosomal proteins and microtubule organization depends on PCM-1

17 March 2017

1 reference

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Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

17 March 2017

1 reference

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Evidence for the involvement of Tiam1 in axon formation

17 March 2017

1 reference

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A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system

17 March 2017

1 reference

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Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1

17 March 2017

1 reference

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Centriolar satellites: molecular characterization, ATP-dependent movement toward centrioles and possible involvement in ciliogenesis

17 March 2017

1 reference

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Dynactin is required for microtubule anchoring at centrosomes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Graded reduction of Pafah1b1 (Lis1) activity results in neuronal migration defects and early embryonic lethality

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

17 March 2017

1 reference

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PCM-1, A 228-kD centrosome autoantigen with a distinct cell cycle distribution

17 March 2017

1 reference

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PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Cortical dynein controls microtubule dynamics to generate pulling forces that position microtubule asters

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Nectins establish a checkerboard-like cellular pattern in the auditory epithelium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Kif3a regulates planar polarization of auditory hair cells through both ciliary and non-ciliary mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Principles of planar polarity in animal development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

A truncating mutation in GPSM2 is associated with recessive non-syndromic hearing loss

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish

29 September 2017

1 reference

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Lissencephaly: mechanistic insights from animal models and potential therapeutic strategies

29 September 2017

1 reference

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Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Generation and characterization of Atoh1-Cre knock-in mouse line

29 September 2017

1 reference

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Actin-bundling protein TRIOBP forms resilient rootlets of hair cell stereocilia essential for hearing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

LIS1 and NudE induce a persistent dynein force-producing state

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Symmetry breaking in the life cycle of the budding yeast

29 September 2017

1 reference

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Shaping fission yeast with microtubules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Motor- and tail-dependent targeting of dynein to microtubule plus ends and the cell cortex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

The cellular roles of the lissencephaly gene LIS1, and what they tell us about brain development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Dictyostelium LIS1 is a centrosomal protein required for microtubule/cell cortex interactions, nucleus/centrosome linkage, and actin dynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Lis1 and doublecortin function with dynein to mediate coupling of the nucleus to the centrosome in neuronal migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Construction of centrosomes and spindle poles by molecular motor-driven assembly of protein particles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Differential phosphorylation in vivo of cytoplasmic dynein associated with anterogradely moving organelles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Selective stabilization of microtubules oriented toward the direction of cell migration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

The structure of the cuticular plate, an in vivo actin gel.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Actin filaments, stereocilia, and hair cells: how cells count and measure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Functional interplay between LIS1, NDE1 and NDEL1 in dynein-dependent organelle positioning.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Rational design and applications of a Rac GTPase-specific small molecule inhibitor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Tubulin and microtubules in cochlear hair cells: comparative immunocytochemistry and ultrastructure

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Coupling of cortical dynein and G alpha proteins mediates spindle positioning in Caenorhabditis elegans

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

How dynein helps the cell find its center: a servomechanical model.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Transgenic mouse line with green-fluorescent protein-labeled Centrin 2 allows visualization of the centrosome in living cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3621493

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23533177

12 December 2020

inferred from PubMed ID database lookup

Multiple modes of cytoplasmic dynein regulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23533177

12 December 2020

inferred from PubMed ID database lookup

Establishment of hair bundle polarity and orientation in the developing vestibular system of the mouse

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23533177

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1242/DEV.089763

1 reference

24 June 2017

0 references

1 reference