Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver (Q28586412)

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11 November 2019

title

Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver (English)

2 references

31 January 2017

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11 November 2019

main subject

brain

0 references

Prenylcysteine oxidase 1

1 reference

GOA release 2020-03-11

author

Stephen G. Young

9

1 reference

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11 November 2019

1

Anne Beigneux

2 references

31 January 2017

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11 November 2019

2

Shannon K Withycombe

1 reference

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11 November 2019

author name string

Martin Bergo

7

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31 January 2017

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11 November 2019

Jennifer A Digits

3

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11 November 2019

William R Tschantz

4

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11 November 2019

Carolyn A Weinbaum

5

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11 November 2019

Stephen M Griffey

6

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11 November 2019

Patrick J Casey

8

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11 November 2019

language of work or name

English

0 references

publication date

31 July 2002

1 reference

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Journal of Biological Chemistry

11 November 2019

published in

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volume

277

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issue

41

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page(s)

38358-38363

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Protein prenyltransferases

11 November 2019

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1 reference

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Protein prenylation: molecular mechanisms and functional consequences

21 January 2018

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Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A

21 January 2018

1 reference

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Isolation and characterization of a prenylcysteine lyase from bovine brain

21 January 2018

1 reference

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Cloning, expression, and cellular localization of a human prenylcysteine lyase

21 January 2018

1 reference

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Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase

21 January 2018

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Characterization of prenylcysteines that interact with P-glycoprotein and inhibit drug transport in tumor cells

21 January 2018

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Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis

21 January 2018

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Targeted inactivation of the isoprenylcysteine carboxyl methyltransferase gene causes mislocalization of K-Ras in mammalian cells

21 January 2018

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The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

21 January 2018

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Production of homozygous mutant ES cells with a single targeting construct

21 January 2018

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Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

21 January 2018

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Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

21 January 2018

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Molecular cloning and expression of palmitoyl-protein thioesterase 2 (PPT2), a homolog of lysosomal palmitoyl-protein thioesterase with a distinct substrate specificity

21 January 2018

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Protein prenylcysteine analog inhibits agonist-receptor-mediated signal transduction in human platelets

21 January 2018

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Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase

21 January 2018

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Biochemical, cellular, and pharmacological aspects of the multidrug transporter

21 January 2018

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Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils

21 January 2018

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On the mechanism of the inhibition of transducin function by farnesylcysteine analogs

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M205183200

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12151402%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

2 references

31 January 2017