Bcl11b is required for differentiation and survival of αβ T lymphocytes (Q28592191)

31 January 2017

title

Bcl11b is required for differentiation and survival of alphabeta T lymphocytes (English)

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31 January 2017

Bcl11b is required for differentiation and survival of αβ T lymphocytes (English)

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B cell leukemia/lymphoma 11B

28 December 2023

main subject

lymphocyte

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GOA release 2020-03-11

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28 December 2023

6

Yukio Mishima

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31 January 2017

Yuichi Wakabayashi

1

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31 January 2017

Hisami Watanabe

2

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31 January 2017

Jun Inoue

3

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31 January 2017

Naoki Takeda

4

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31 January 2017

Jun Sakata

5

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31 January 2017

Jiro Hitomi

7

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31 January 2017

Takashi Yamamoto

8

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31 January 2017

Masanori Utsuyama

9

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31 January 2017

Ohtsura Niwa

10

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31 January 2017

Shinichi Aizawa

11

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31 January 2017

Ryo Kominami

12

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31 January 2017

language of work or name

English

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publication date

1 June 2003

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31 January 2017

28 April 2003

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12717433

full work available at URL

28 December 2023

http://www.nature.com/articles/ni927.pdf

file format

Portable Document Format

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http://www.nature.com/articles/ni927

28 December 2023

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28 December 2023

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31 January 2017

volume

4

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31 January 2017

issue

6

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31 January 2017

page(s)

533–539

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Natural and engineered disorders of lymphocyte development

31 January 2017

cites work

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Pleiotropic changes controlled by the pre-T-cell receptor

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Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

21 January 2018

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The CD3gamma chain is essential for development of both the TCRalphabeta and TCRgammadelta lineages

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An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.

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Profound block in thymocyte development in mice lacking p56lck

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Defective T cell development and function in calcineurin A beta -deficient mice

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WNT signaling and lymphocyte development

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Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development.

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Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

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FADD/MORT1 regulates the pre-TCR checkpoint and can function as a tumour suppressor

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p53 prevents maturation to the CD4+CD8+ stage of thymocyte differentiation in the absence of T cell receptor rearrangement.

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The BCL11 gene family: involvement of BCL11A in lymphoid malignancies

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Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors

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p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

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Bclx regulates the survival of double-positive thymocytes

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

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Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements

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Enhancer-dependent and -independent steps in the rearrangement of a human T cell receptor delta transgene.

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A role for histone acetylation in the developmental regulation of VDJ recombination.

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COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein

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T cell-specific FADD-deficient mice: FADD is required for early T cell development

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Early thymocyte development is regulated by modulation of E2A protein activity

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Induction of apoptosis in fibroblasts by c-myc protein

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Effects of an Rb mutation in the mouse

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Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.

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RB-dependent S-phase response to DNA damage

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Evi9 encodes a novel zinc finger protein that physically interacts with BCL6, a known human B-cell proto-oncogene product

21 January 2018

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Bcl11a is essential for normal lymphoid development

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Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

21 January 2018

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c-kit+ stem cells and thymocyte precursors in the livers of adult mice

21 January 2018

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Cell kinetic study of normal human bone marrow hematopoiesis and acute leukemia using 7AAD/PY

21 January 2018

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Crucial role of the pre-T-cell receptor α gene in development of ap but not γδ T cells

21 January 2018

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Constitutive pre-TCR signaling promotes differentiation through Ca2+ mobilization and activation of NF-kappaB and NFAT

21 January 2018

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7 January 2021

A nonredundant role for the adapter protein Shc in thymic T cell development

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7 January 2021

The beta-catenin--TCF-1 pathway ensures CD4(+)CD8(+) thymocyte survival

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7 January 2021

Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells

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7 January 2021

Allelic loss mapping and physical delineation of a region harboring a putative thymic lymphoma suppressor gene on mouse chromosome 12

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7 January 2021

Homozygous deletions and point mutations of the Rit1/Bcl11b gene in gamma-ray induced mouse thymic lymphomas

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7 January 2021

A matter of life and cell death

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7 January 2021

Inhibition of T-cell receptor beta-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck

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