Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease (Q28592609)

Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli

GOA release 2020-03-11

cystic kidney disease

1 reference

Julie A. Jonassen

1

1 reference

31 January 2017

Jovenal San Agustin

series ordinal

2

1 reference

31 January 2017

John A. Follit

series ordinal

3

1 reference

31 January 2017

Gregory J. Pazour

series ordinal

4

1 reference

31 January 2017

language of work or name

English

0 references

publication date

3 November 2008

1 reference

31 January 2017

Journal of Cell Biology

1 reference

31 January 2017

183

1 reference

31 January 2017

3

1 reference

31 January 2017

377–384

1 reference

31 January 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

17 March 2017

Intraflagellar transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

beta-catenin signaling and cancer

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Overview of structure and function of mammalian cilia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Protamine-Cre recombinase transgenes efficiently recombine target sequences in the male germ line of mice, but not in embryonic stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

TRPP2 and TRPV4 form a polymodal sensory channel complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Disruption of intraflagellar transport in adult mice leads to obesity and slow-onset cystic kidney disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Molecular regulation of kidney development: is the answer blowing in the Wnt?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

A role for a novel centrosome cycle in asymmetric cell division

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Polycystic kidney disease: cell division without a c(l)ue?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Intraflagellar transport and cilia-dependent renal disease: the ciliary hypothesis of polycystic kidney disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

29 September 2017

Intraflagellar Transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Genetics and pathogenesis of polycystic kidney disease.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Bending the MDCK cell primary cilium increases intracellular calcium

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Beta-catenin is necessary to keep cells of ureteric bud/Wolffian duct epithelium in a precursor state

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575779

Defective planar cell polarity in polycystic kidney disease

3 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200808137

Renal malformations may be linked to mutations in the hepatocyte nuclear factor-1alpha (MODY3) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200808137

Functionally unequal centrosomes drive spindle orientation in asymmetrically dividing Drosophila neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200808137

Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200808137

Widespread recombinase expression using FLPeR (flipper) mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18981227

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Early development of polycystic kidney disease in transgenic mice expressing an activated mutant of the beta-catenin gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18981227

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The atypical Rho family GTPase Wrch-1 regulates focal adhesion formation and cell migration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18981227

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.200808137

1 reference

3304334

3304334

1 reference

1 reference

1 reference