Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma (Q28593632)

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12 February 2020

title

Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906996%20AND%20SRC:MED&resulttype=core&format=json

Phosphoinositide-3-kinase regulatory subunit 5

12 February 2020

main subject

1 reference

GOA release 2020-03-11

author

Matthias P Wymann

10

1 reference

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12 February 2020

Bernd Nürnberg

12

1 reference

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author name string

Barbara Kurig

1

2 references

31 January 2017

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12 February 2020

Aliaksei Shymanets

2

2 references

31 January 2017

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12 February 2020

Thomas Bohnacker

3

2 references

31 January 2017

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12 February 2020

Carsten Brock

5

2 references

31 January 2017

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12 February 2020

Michael Schaefer

7

2 references

31 January 2017

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12 February 2020

Antje Gohla

8

2 references

31 January 2017

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12 February 2020

Christian Harteneck

9

2 references

31 January 2017

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12 February 2020

Elisabeth Jeanclos

11

2 references

31 January 2017

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12 February 2020

Prajwal

4

1 reference

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12 February 2020

Mohammad Reza Ahmadian

6

1 reference

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12 February 2020

language of work or name

English

0 references

publication date

11 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906996%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

12 February 2020

published in

2 references

31 January 2017

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12 February 2020

volume

106

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12 February 2020

issue

48

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12 February 2020

page(s)

20312-20317

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906996%20AND%20SRC:MED&resulttype=core&format=json

Targeting phosphoinositide 3-kinase: moving towards therapy

12 February 2020

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p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma

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Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma

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Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

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Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras

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The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

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Pasteurella multocida toxin activates Gbetagamma dimers of heterotrimeric G proteins

29 September 2017

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The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.

29 September 2017

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29 September 2017

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Deletion of the phosphoinositide 3-kinase p110gamma gene attenuates murine atherosclerosis

29 September 2017

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Antigen receptor signalling: a distinctive role for the p110delta isoform of PI3K.

29 September 2017

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29 September 2017

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Characterization of p87PIKAP, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B.

29 September 2017

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Phosphoinositide 3-kinase gamma: a key modulator in inflammation and allergy

29 September 2017

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Identification and characterization of the autophosphorylation sites of phosphoinositide 3-kinase isoforms beta and gamma

29 September 2017

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Activation of phosphoinositide 3-kinase gamma by Ras.

29 September 2017

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29 September 2017

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21 January 2018

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Phosphoinositide 3-kinase isoforms selectively couple receptors to vascular L-type Ca(2+) channels

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils

21 January 2018

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21 January 2018

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27 November 2018

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27 November 2018

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27 November 2018

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Individual Rate Constants for the Interaction of Ras Proteins with GTPase-Activating Proteins Determined by Fluorescence Spectroscopy

27 November 2018

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12 December 2020

Heterodimeric phosphoinositide 3-kinase consisting of p85 and p110beta is synergistically activated by the betagamma subunits of G proteins and phosphotyrosyl peptide

1 reference

12 December 2020

Roles of non-catalytic subunits in gbetagamma-induced activation of class I phosphoinositide 3-kinase isoforms beta and gamma

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12 December 2020

Finding Partners for PI3K : When 84 Is Better Than 101

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0905506106

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906996%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

ADS bibcode

2009PNAS..10620312K

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19906996%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

2 references