Ablation of dihydroceramide desaturase confers resistance to etoposide-induced apoptosis in vitro (Q28595077)

GOA release 2020-03-11

7

Markus R. Wenk

1 reference

1 February 2017

8

Scott A. Summers

1 reference

1 February 2017

Monowarul M. Siddique

1

1 reference

1 February 2017

Benjamin T. Bikman

2

1 reference

1 February 2017

Liping Wang

3

1 reference

1 February 2017

Li Ying

4

1 reference

1 February 2017

Erin Reinhardt

5

1 reference

1 February 2017

Guanghou Shui

Creative Commons CC0 License

6

1 reference

1 February 2017

language of work or name

English

0 references

publication date

1 January 2012

1 reference

1 February 2017

1 reference

1 February 2017

7

1 reference

1 February 2017

9

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1 February 2017

e44042

1 reference

1 February 2017

start time

11 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling

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N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing

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Involvement of dihydroceramide desaturase in cell cycle progression in human neuroblastoma cells

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Ceramides and other bioactive sphingolipid backbones in health and disease: lipidomic analysis, metabolism and roles in membrane structure, dynamics, signaling and autophagy

29 September 2017

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Loss of sphingosine kinase-1 activates the intrinsic pathway of programmed cell death: modulation of sphingolipid levels and the induction of apoptosis.

29 September 2017

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29 September 2017

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29 September 2017

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Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

29 September 2017

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Identification of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation

29 September 2017

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Ceramide accumulation precedes caspase-3 activation during apoptosis of A549 human lung adenocarcinoma cells

29 September 2017

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Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells

29 September 2017

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De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway

29 September 2017

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PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model

29 September 2017

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A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.

29 September 2017

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Wild-type p53-dependent etoposide-induced apoptosis mediated by caspase-3 activation in human glioma cells

29 September 2017

1 reference

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Ceramide in the eukaryotic stress response

29 September 2017

1 reference

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Mass spectrometric identification of increased C16 ceramide levels during apoptosis

29 September 2017

1 reference

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The role of sphingosine in cell growth regulation and transmembrane signaling

29 September 2017

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The sphingomyelin cycle and the second messenger function of ceramide.

29 September 2017

1 reference

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DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3439484

Ceramide activates heterotrimeric protein phosphatase 2A.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3439484

Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3439484

Dihydrosphingomyelin Impairs HIV-1 Infection by Rigidifying Liquid-Ordered Membrane Domains

28 July 2018

1 reference

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The proapoptotic C16-ceramide-dependent pathway requires the death-promoting factor Btf in colon adenocarcinoma cells.

27 November 2018

1 reference

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Dihydroceramide intracellular increase in response to resveratrol treatment mediates autophagy in gastric cancer cells.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3439484

p53 is required for etoposide-induced apoptosis of human embryonic stem cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3439484

Oleate reverses palmitate-induced insulin resistance and inflammation in skeletal muscle cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3439484

Mitochondrial ceramide increases in UV-irradiated HeLa cells and is mainly derived from hydrolysis of sphingomyelin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3439484

p53 regulates ceramide formation by neutral sphingomyelinase through reactive oxygen species in human glioma cells

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3439484

Elevation of ceramide within distal neurites inhibits neurite growth in cultured rat sympathetic neurons

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22984457

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

De novo C16- and C24-ceramide generation contributes to spontaneous neutrophil apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22984457