High-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH region (Q28709119)

2

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Suzanne Avis

3

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Ashleigh Binnie

4

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Jeanette Dilley

5

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Xi Yang

6

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Kevin Lindquist

7

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Séverine Ménoret

8

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Anne-Laure Iscache

9

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Laure-Hélène Ouisse

10

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Arvind Rajpal

11

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Ignacio Anegon

12

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Michael S Neuberger

13

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Roland Buelow

14

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Marianne Brüggemann

A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

15

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language of work or name

English

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publication date

15 February 2013

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published in

Journal of Immunology

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volume

190

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page(s)

1481-90

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issue

4

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cites work

1 reference

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Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases

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Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice

17 March 2017

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Knockout rats via embryo microinjection of zinc-finger nucleases

17 March 2017

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Reshaping human antibodies for therapy

17 March 2017

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Antigen and cytokine receptor signals guide the development of the naïve mature B cell repertoire

17 March 2017

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Memory B cell antibodies to HIV-1 gp140 cloned from individuals infected with clade A and B viruses

3 June 2018

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Human monoclonal antibodies to HIV-1 gp140 from mice bearing YAC-based human immunoglobulin transloci

3 June 2018

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Therapeutic antibodies for autoimmunity and inflammation

3 June 2018

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Next generation immunotherapeutics--honing the magic bullet

3 June 2018

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Fully human antibodies from transgenic mouse and phage display platforms

3 June 2018

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Protocols for cytogenetic studies of human embryonic stem cells

3 June 2018

1 reference

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Fc-receptors as regulators of immunity.

3 June 2018

1 reference

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Transcription of a productively rearranged Ig VDJC alpha does not require the presence of HS4 in the IgH 3' regulatory region

3 June 2018

1 reference

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A family of glycosylphosphatidylinositol-linked aspartyl proteases is required for virulence of Candida glabrata

3 June 2018

1 reference

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Human antibodies from transgenic animals

3 June 2018

1 reference

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Production of human monoclonal and polyclonal antibodies in TransChromo animals

3 June 2018

1 reference

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Novel control motif cluster in the IgH delta-gamma 3 interval exhibits B cell-specific enhancer function in early development

3 June 2018

1 reference

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Antibody engineering via genetic engineering of the mouse: XenoMouse strains are a vehicle for the facile generation of therapeutic human monoclonal antibodies

3 June 2018

1 reference

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A human immunoglobulin lambda locus is similarly well expressed in mice and humans

3 June 2018

1 reference

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Transgenic mice containing a human heavy chain immunoglobulin gene fragment cloned in a yeast artificial chromosome

3 June 2018

1 reference

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Serum immunoglobulin G subclass concentrations in periodontally healthy and diseased individuals

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Creation of mice expressing human antibody light chains by introduction of a yeast artificial chromosome containing the core region of the human immunoglobulin kappa locus.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Characterization of the 'unusual' mobility of large circular DNAs in pulsed field-gradient electrophoresis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

pYAC-RC, a yeast artificial chromosome vector for cloning DNA cut with infrequently cutting restriction endonucleases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

The immunogenicity of chimeric antibodies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

A repertoire of monoclonal antibodies with human heavy chains from transgenic mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

A matched set of rat/mouse chimeric antibodies. Identification and biological properties of rat H chain constant regions mu, gamma 1, gamma 2a, gamma 2b, gamma 2c, epsilon, and alpha

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Targeted alterations in yeast artificial chromosomes for inter-species gene transfer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Recovery of DNA from agarose gels using a modified Elutrap

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Characterization of immunoglobulin heavy chain knockout rats.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Antibody repertoires of four- and five-feature translocus mice carrying human immunoglobulin heavy chain and kappa and lambda light chain yeast artificial chromosomes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Antibody expression from the core region of the human IgH locus reconstructed in transgenic mice using bacteriophage P1 clones

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

The mouse IgH 3'-enhancer.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Human antibody production in transgenic mice: expression from 100 kb of the human IgH locus

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3566577

Cloned transchromosomic calves producing human immunoglobulin

27 November 2018

1 reference

12 December 2020

Rat immunoglobulins in serum and secretions: Purification of rat IgM, IgA, and IgG and their quantitation in serum, colostrum, milk and saliva

1 reference

12 December 2020

Novel antibodies by DNA manipulation

1 reference

12 December 2020

Antigen-specific human antibodies from mice comprising four distinct genetic modifications

1 reference

12 December 2020

A novel method of preparing rat-monoclonal antibody-producing hybridomas by using rat medial iliac lymph node cells

1 reference

12 December 2020

Assembly and extension of yeast artificial chromosomes to build up a large locus

1 reference

12 December 2020

Interallelic Class Switch Recombination Contributes Significantly to Class Switching in Mouse B Cells

1 reference

12 December 2020

Preparation of intact yeast artificial chromosome DNA for transgenesis of mice

1 reference

12 December 2020

Three classes and four (sub)classes of rat immunoglobulins: IgM, IgA, IgE and IgG1, IgG2a, IgG2b, IgG2c

1 reference

12 December 2020

Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination

1 reference

12 December 2020