A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma (Q28731711)

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scientific article (publication date: 2012)

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English	A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma	scientific article (publication date: 2012)

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A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma (English)

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1 reference

based on heuristic

1 reference

based on heuristic

object named as

April Coan

11

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Henry Seth Friedman

9

object named as

Henry S Friedman

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Darell D. Bigner

15

object named as

Darell D Bigner

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Annick Desjardins

7

object named as

Annick Desjardins

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8

object named as

Allan H Friedman

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David A Reardon

13

object named as

David A Reardon

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Roger E McLendon

12

object named as

Roger E McLendon

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James J Vredenburgh

14

object named as

James J Vredenburgh

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James H. Herndon

10

object named as

James E Herndon

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Robert J Schmittling

2

object named as

Robert J Schmittling

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Kendra L Congdon

4

object named as

Kendra L Congdon

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5

object named as

Smita K Nair

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Duane A Mitchell

16

object named as

Duane A Mitchell

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author name string

John H Sampson

1

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Gary E Archer

3

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Elizabeth A Reap

6

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publication date

2012

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7

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2

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e31046

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copyright license

Creative Commons Attribution 4.0 International

27 February 2012

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April 2022 Public Data File from Crossref

copyright status

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A function for interleukin 2 in Foxp3-expressing regulatory T cells

1 reference

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors

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Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans

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Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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21 January 2018

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21 January 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daclizumab (Zenapax) inhibits early interleukin-2 receptor signal transduction events

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific suppressor T cells involved in self-tolerance are activated extrathymically by self-antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daclizumab: outcome of phase III trials and mechanism of action. Double Therapy and the Triple Therapy Study Groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383993

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based on heuristic

inferred from PubMed ID database lookup

Fueling regulation: IL-2 keeps CD4+ Treg cells fit

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383993

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based on heuristic

inferred from PubMed ID database lookup

Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22383993

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0031046

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Consolidated OpenCitations Corpus – April 2017

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2012PLoSO...731046S

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Consolidated OpenCitations Corpus – April 2017

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