AMP-activated protein kinase (AMPK) mediates nutrient regulation of thioredoxin-interacting protein (TXNIP) in pancreatic beta-cells (Q28741436)

1

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Mali Ketzinel-Gilad

2

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Erol Cerasi

3

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Nurit Kaiser

4

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Gil Leibowitz

Creative Commons Attribution 4.0 International

5

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language of work or name

English

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publication date

2011

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published in

PLOS One

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volume

6

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issue

12

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page(s)

e28804

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copyright license

start time

14 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Cyclic AMP signaling stimulates proteasome degradation of thioredoxin interacting protein (TxNIP) in pancreatic beta-cells

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Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes

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Inhibition of AMP-activated protein kinase protects pancreatic beta-cells from cytokine-mediated apoptosis and CD8+ T-cell-induced cytotoxicity.

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TXNIP regulates peripheral glucose metabolism in humans

3 June 2018

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Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion

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3 June 2018

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AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase

3 June 2018

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3 June 2018

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3 June 2018

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Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function

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AMP-activated protein kinase agonist dose dependently improves function and reduces apoptosis in glucotoxic beta-cells without changing triglyceride levels

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AICA-riboside induces apoptosis of pancreatic beta cells through stimulation of AMP-activated protein kinase

21 January 2018

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Glucose-induced repression of PPAR gene expression in pancreatic -cells involves PP2A activation and AMPK inactivation

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Palmitate activates AMP-activated protein kinase and regulates insulin secretion from beta cells

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22194917

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Monolayer culture of adult rat pancreatic islets on extracellular matrix: long term maintenance of differentiated B-cell function

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