Enhancement of mesenteric artery contraction to 5-HT depends on Rho kinase and Src kinase pathways in the ob/ob mouse model of type 2 diabetes (Q28749389)

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scientific article (publication date: July 2010)

Language	Label	Description	Also known as
English	Enhancement of mesenteric artery contraction to 5-HT depends on Rho kinase and Src kinase pathways in the ob/ob mouse model of type 2 diabetes	scientific article (publication date: July 2010)

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scholarly article

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Enhancement of mesenteric artery contraction to 5-HT depends on Rho kinase and Src kinase pathways in the ob/ob mouse model of type 2 diabetes (English)

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type 2 diabetes

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author name string

Takayuki Matsumoto

1

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Tsuneo Kobayashi

2

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Keiko Ishida

3

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Kumiko Taguchi

4

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Katsuo Kamata

5

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language of work or name

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publication date

July 2010

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British Journal of Pharmacology

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160

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5

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1092-104

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Diabetic state, high plasma insulin and angiotensin II combine to augment endothelin-1-induced vasoconstriction via ETA receptors and ERK

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Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity

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Crystal structures of c-Src reveal features of its autoinhibitory mechanism

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Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase

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Cellular functions regulated by Src family kinases

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7 April 2017

Sex-dependent differences in Rho activation contribute to contractile dysfunction in type 2 diabetic mice

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3 June 2018

Role of nitrosative stress in the pathogenesis of diabetic vascular dysfunction

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3 June 2018

Mechanisms of augmented vasoconstriction induced by 5-hydroxytryptamine in aortic rings from spontaneously hypertensive rats

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3 June 2018

Pulmonary hypertension: therapeutic targets within the serotonin system.

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3 June 2018

The expression and function of Ca(2+)-sensing receptors in rat mesenteric artery; comparative studies using a model of type II diabetes

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3 June 2018

Oxidative stress and COX cause hyper-responsiveness in vascular smooth muscle of the femoral artery from diabetic rats.

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3 June 2018

Thiazolidinediones: effects on insulin resistance and the cardiovascular system

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3 June 2018

Effects of alpha-lipoic acid on endothelial function in aged diabetic and high-fat fed rats.

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3 June 2018

Mechanisms underlying lysophosphatidylcholine-induced potentiation of vascular contractions in the Otsuka Long-Evans Tokushima Fatty (OLETF) rat aorta

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3 June 2018

Rho-kinase is an important therapeutic target in cardiovascular medicine

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3 June 2018

5-HT in systemic hypertension: foe, friend or fantasy?

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3 June 2018

Functions of 5-HT2A receptor and its antagonists in the cardiovascular system

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3 June 2018

Augmented contractile response of vascular smooth muscle in a diabetic mouse model

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3 June 2018

The role of 5-HT on the cardiovascular and renal systems and the clinical potential of 5-HT modulation

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3 June 2018

Serotonin receptor blockade improves distal perfusion after lower limb ischemia in the fatty Zucker rat.

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3 June 2018

Coupling of c-Src to large conductance voltage- and Ca2+-activated K+ channels as a new mechanism of agonist-induced vasoconstriction

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3 June 2018

Characterization of the serotonin receptor mediating contraction in the mouse thoracic aorta and signal pathway coupling.

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3 June 2018

Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells.

1 reference

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3 June 2018

Reduction of obesity, as induced by leptin, reverses endothelial dysfunction in obese (Lep(ob)) mice

1 reference

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3 June 2018

Endothelial dysfunction in diabetes.

1 reference

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3 June 2018

Supersensitivity of atherosclerotic rabbit aorta to ergonovine. Mediation by a serotonergic mechanism

1 reference

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3 June 2018

A contrasting effect of the diabetic state upon the contractile responses of aortic preparations from the rat and rabbit.

1 reference

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3 June 2018

Impairment of endothelium-dependent relaxation and changes in levels of cyclic GMP in aorta from streptozotocin-induced diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936019

3 June 2018

Analysis of the depressant effect of the endothelium on contractions of rabbit isolated basilar artery to 5-hydroxytryptamine

1 reference

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3 June 2018

c-Src tyrosine kinase, a critical component for 5-HT2A receptor-mediated contraction in rat aorta

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https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00753.X

21 January 2018

Alterations in EDHF-type relaxation and phosphodiesterase activity in mesenteric arteries from diabetic rats

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https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00753.X

21 January 2018

Gender differences in vascular reactivity to endothelin-1 (1-31) in mesenteric arteries from diabetic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00753.X

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Metformin normalizes endothelial function by suppressing vasoconstrictor prostanoids in mesenteric arteries from OLETF rats, a model of type 2 diabetes

1 reference

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21 January 2018

Involvement of NO and MEK/ERK pathway in enhancement of endothelin-1-induced mesenteric artery contraction in later-stage type 2 diabetic Goto-Kakizaki rat.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00753.X

21 January 2018

Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways.

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21 January 2018

Involvement of Src family protein tyrosine kinases in Ca(2+) sensitization of coronary artery contraction mediated by a sphingosylphosphorylcholine-Rho-kinase pathway

1 reference

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RhoA activation contributes to sex differences in vascular contractions.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00753.X

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Sarpogrelate hydrochloride, a serotonin2A receptor antagonist, reduces albuminuria in diabetic patients with early-stage diabetic nephropathy

1 reference

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21 January 2018

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21 January 2018

Guide to Receptors and Channels (GRAC), 4th Edition

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27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936019

27 November 2018

Vascular responses to agonists in rat mesenteric artery from diabetic rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2936019

27 November 2018

Insulin resistance and hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin-stimulated aortic endothelial cells secrete a novel T lymphocyte chemotactic and growth factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Daily variations of platelet aggregation in relation to blood and plasma serotonin in diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced 5-HT2 receptor mediated contractions in diabetic rat aorta: participation of Ca2+ channels associated with protein kinase C activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serotonin enhances the production of type IV collagen by human mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist-specific impairment of coronary vascular function in genetically altered, hyperlipidemic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apocynin normalizes hyperreactivity to phenylephrine in mesenteric arteries from cholesterol-fed mice by improving endothelium-derived hyperpolarizing factor response

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Imbalance between endothelium-derived relaxing and contracting factors in mesenteric arteries from aged OLETF rats, a model of Type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20590603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2010.00753.X

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

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